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A 64077

Known as: A-64077, Abbot 64077 
 
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
The role of leukotrienes in the pathogenesis of acute gastric ulceration induced by nonsteroidal antiinflammatory drugs was… Expand
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Review
1997
Review
1997
Asthma is a chronic inflammatory disease that is associated with widespread but variable airflow obstruction. The mechanisms that… Expand
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Highly Cited
1997
Highly Cited
1997
Substance P (SP) has been shown to mediate granulocyte infiltration into the mouse skin by inducing mast cell degranulation. In… Expand
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1994
1994
This study was designed to characterize the role of arachidonate 5-lipoxygenase metabolism during experimental intestinal… Expand
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Highly Cited
1993
Highly Cited
1993
BAY X 1005 ((R)-2-[4-(quinolin-2-yl-methoxy)phenyl]-2-cyclopentyl acetic acid) has been demonstrated to be a potent inhibitor of… Expand
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Highly Cited
1991
Highly Cited
1991
It has been suggested that the oxidative modification of low density lipoprotein (LDL) is a key event in atherogenesis. Several… Expand
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Highly Cited
1991
Highly Cited
1991
The effect of a single oral dose (800 mg) of zileuton (A-64077), a specific 5-lipoxygenase inhibitor, on the early and late… Expand
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Highly Cited
1990
Highly Cited
1990
BACKGROUND The enzyme 5-lipoxygenase catalyzes the metabolism of arachidonic acid to form products that have been implicated in… Expand
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Highly Cited
1990
Highly Cited
1990
  • H. Knapp
  • The New England journal of medicine
  • 1990
  • Corpus ID: 23137098
BACKGROUND AND METHODS The clinical importance of leukotrienes in human allergy has not been defined, in part because there have… Expand
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Highly Cited
1990
Highly Cited
1990
Leukotriene B4 (LTB4) and prostaglandin E2 (PGE2) concentrations were measured in rectal dialysis fluid from ten patients with… Expand
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