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A 64077

Known as: A-64077, Abbot 64077 
National Institutes of Health

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zileuton

Papers overview

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2015
2015
A saint, an abbot, his documents and her property: power, reform and landholding in the monastery of Homblières under Abbot Berner (949–82)
The monastery of Homblières, after 949, when it was turned from a community of nuns into a reformed Benedictine monastery under… 
1997
1997
Effects of the 5-lipoxygenase inhibitor A-64077 on intestinal hypothermic organ preservation injury.
The effects of the orally active selective 5-lipoxygenase inhibitor Zileuton (A-64077, (N-1(1-benzo{b}thien-2-ylethyl)-N… 
1994
1994
Effects of the arachidonate 5-lipoxygenase synthesis inhibitor A-64077 in intestinal ischemia-reperfusion injury.
This study was designed to characterize the role of arachidonate 5-lipoxygenase metabolism during experimental intestinal… 
1994
1994
Response of the isolated guinea pig bladder to exogenous and endogenous leukotrienes.
Highly Cited
1992
Highly Cited
1992
Methoxytetrahydropyrans. A new series of selective and orally potent 5-lipoxygenase inhibitors.
Investigation of the SAR of the lead (methoxyalkyl)thiazole 1-[3-(naphth-2-ylmethoxy)phenyl]-1-thiazol-2-ylprop yl methyl ether… 
1992
1992
Phase II study of the safety and efficacy of a 5-lipoxygenase inhibitor in patients with ulcerative colitis.
We examined the effects of an inhibitor of 5-lipoxygenase (A-64077) in 11 patients with mild to moderately active ulcerative… 
1992
1992
Pharmacological investigation of the role of leukotrienes in the pathogenesis of experimental NSAID gastropathy
The role of leukotrienes in the pathogenesis of acute gastric ulceration induced by nonsteroidal antiinflammatory drugs was… 
1992
1992
Platelet‐activating factor synthesis by peritoneal mast cells and its inhibition by two quinoline‐based compounds
1 Peritoneal mast cells from rat were co‐incubated in vitro in a platelet aggregometer cuvette with washed rabbit platelets. In… 
Highly Cited
1991
Highly Cited
1991
Effect of a 5-lipoxygenase inhibitor on leukotriene generation and airway responses after allergen challenge in asthmatic patients.
The effect of a single oral dose (800 mg) of zileuton (A-64077), a specific 5-lipoxygenase inhibitor, on the early and late… 
1991
1991
Effect of Zileuton (A-64077) on the 5-lipoxygenase activity of human whole bloodex vivo
The potency and reversibility of a new orally active 5-lipoxygenase (5-LO) inhibitor were evaluated in human volunteers. Zileuton… 
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