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A 192621

Known as: A-192621, A192621 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Pyrrolidines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Rosiglitazone Attenuated Endothelin-1-Induced Vasoconstriction of Pulmonary Arteries in the Rat Model of Pulmonary Arterial Hypertension via Differential Regulation of ET-1 Receptors
Pulmonary arterial hypertension (PAH) is a fatal disease characterized by a progressive increase in pulmonary arterial pressure… 
2011
2011
Endothelial Endothelin B Receptor-Mediated Prevention of Cerebrovascular Remodeling Is Attenuated in Diabetes Because of Up-Regulation of Smooth Muscle Endothelin Receptors
Structure and function of the cerebrovasculature is critical for ischemic stroke outcome. We showed that diabetes causes… 
Highly Cited
2009
Highly Cited
2009
Mechanisms operated by endothelin ETA and ETB receptors in the trigeminal ganglion contribute to orofacial thermal hyperalgesia induced by infraorbital nerve constriction in rats
2008
2008
Therapeutic effects of endothelin-A receptor antagonist on bladder overactivity in rats with chronic spinal cord injury.
Highly Cited
2002
Highly Cited
2002
Pharmacology of endothelin receptor antagonists ABT-627, ABT-546, A-182086 and A-192621: ex vivo and in vivo studies.
Endothelins (ETs), 21-amino-acid peptides involved in the pathogenesis of various diseases, bind to ET(A) and ET(B) receptors to… 
2002
2002
Pharmacology of endothelin receptor antagonists ABT-627, ABT-546, A-182086 and A-192621: in vitro studies.
Endothelins (ETs), 21-amino-acid peptides involved in the pathogenesis of various diseases, bind to ET(A) and ET(B) receptors to… 
2002
2002
Role of endothelin ET(B) receptors in the renal hemodynamic and excretory responses to big endothelin-1.
2000
2000
Type A, but not type B, endothelin receptor antagonists significantly decrease portal pressure in portal hypertensive rats.
Highly Cited
2000
Highly Cited
2000
Upregulation of endothelin B receptors in kidneys of DOCA-salt hypertensive rats.
Experiments were designed to elucidate the role of endothelin B receptors (ET(B)) on arterial pressure and renal function in… 
1999
1999
Effects on haemodynamics by selective endothelin ET(B) receptor and combined endothelin ET(A)/ET(B) receptor antagonism during endotoxin shock.
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