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8-bromo-2'-deoxyadenosine

Known as: 2'-deoxy-8-bromoadenosine, 8-B-2-DA 
 
National Institutes of Health

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1 relation

Broader (1)

Deoxyadenosines

Papers overview

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2011
2011
Mutational specificities of brominated DNA adducts catalyzed by human DNA polymerases.
Chronic inflammation is known to lead to an increased risk for the development of cancer. Under inflammatory condition, cellular… Expand
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2008
2008
The fate of C5' radicals of purine nucleosides under oxidative conditions.
The factors that influence the reactivity of C5' radicals in purine moieties under aerobic conditions are unknown not only in DNA… Expand
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2007
2007
An efficient method for the construction of functionalized DNA bearing amino acid groups through cross-coupling reactions of nucleoside triphosphates followed by primer extension or PCR.
Single-step aqueous cross-coupling reactions of nucleobase-halogenated 2'-deoxynucleosides (8-bromo-2'-deoxyadenosine, 7-iodo-7… Expand
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2005
2005
Inhibitory effects of the guanine moiety on Suzuki couplings of unprotected halonucleosides in aqueous media.
In the Suzuki arylations of unprotected halonucleosides in aqueous media, 8-bromo-2'-deoxyguanosine (8BrdG) couplings were slower… Expand
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2004
2004
The photochemistry of 8-bromo-2'-deoxyadenosine. A direct entry to cyclopurine lesions.
The UV photolysis of 8-bromo-2'-deoxyadenosine has been investigated in different solvents and in the presence of additives like… Expand
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2003
2003
Model studies of DNA C5' radicals. Selective generation and reactivity of 2'-deoxyadenosin-5'-yl radical.
The reaction of hydrated electrons (e(aq)(-)) with 8-bromo-2'-deoxyadenosine has been investigated by radiolytic methods coupled… Expand
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2003
2003
Convenient synthesis of 8-amino-2'-deoxyadenosine.
We studied the behaviour of 8-azido-2'-deoxyadenosine and 8-bromo-2'-deoxyadenosine in aqueous solutions of ammonia and primary… Expand
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2003
2003
Efficient one-step Suzuki arylation of unprotected halonucleosides, using water-soluble palladium catalysts.
Modification of nucleosides to give pharmaceutically active compounds, mutagenesis models, and oligonucleotide structural probes… Expand
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1996
1996
Synthesis and characterization of 8-methoxy-2'- deoxyadenosine-containing oligonucleotides to probe the syn glycosidic conformation of 2'-deoxyadenosine within DNA.
The synthesis of 8-methoxy-2'-deoxyadenosine (moA) protected at N6 as an N,N-dimethylformamidine derivative and incorporation of… Expand
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1994
1994
Synthesis and antiviral activities of 8-alkynyl-, 8-alkenyl-, and 8-alkyl-2'-deoxyadenosine analogues.
Palladium-catalyzed cross-coupling of 8-bromo-2'-deoxyadenosine with terminal alkynes in the presence of copper(I) iodide in… Expand
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