• Publications
  • Influence
A novel p34(cdc2)-binding and activating protein that is necessary and sufficient to trigger G(2)/M progression in Xenopus oocytes.
TLDR
The cloning of two novel cDNAs that when expressed in oocytes induce meiotic maturation efficiently are reported, which identify a novel p34(cdc2) binding and activating protein that regulates the G(2)/M transition during oocyte maturation.
The structure of plasmid‐encoded transcriptional repressor CopG unliganded and bound to its operator
TLDR
The structure of the 45 amino acid transcriptional repressor, CopG, has been solved unliganded and bound to its target operator DNA, and it is revealed that the bihelical region of CopG has a role in oligomerization instead of DNA recognition.
Biochemical basis of SOS-induced mutagenesis in Escherichia coli: reconstitution of in vitro lesion bypass dependent on the UmuD'2C mutagenic complex and RecA protein.
TLDR
Observations provide a biochemical basis for the role of the Umu complex in SOS-targeted and SOS-untargeted mutagenesis and its ability to stimulate both nucleotide misincorporation and mismatch extension at aberrant and normal template sites.
Transgenic Rice Plants Expressing the Antifungal AFP Protein from Aspergillus Giganteus Show Enhanced Resistance to the Rice Blast Fungus Magnaporthe Grisea
TLDR
Results presented here indicate that AFP can be functionally expressed in rice plants for protection against the rice blast fungus M. grisea.
Crystal structure of a DNA Holliday junction
TLDR
The crystal structure of a four-way DNA junction is determined by multiwavelength anomalous diffraction, and it is refined to 2.16 Å resolution, implying that a conformational change must occur for the junction to branch-migrate or isomerize.
Label-free DNA biosensors based on functionalized carbon nanotube field effect transistors.
TLDR
A carbon nanotube transistor array was used to detect DNA hybridization and a new approach to ensure specific adsorption of DNA to the nanotubes was developed, resulting in significant changes in key transistor parameters.
Nanotechnology: Carbon nanotubes with DNA recognition
TLDR
This work unifies single-walled carbon nanotubes with the specific molecular-recognition features of DNA by coupling SWNTs to peptide nucleic acid (PNA, an uncharged DNA analogue) and hybridizing these macromolecular wires with complementary DNA.
Abasic translesion synthesis by DNA polymerase beta violates the "A-rule". Novel types of nucleotide incorporation by human DNA polymerase beta at an abasic lesion in different sequence contexts.
TLDR
The misaligned DNA structures generated during dNTP-stabilized lesion bypass do not conform to misaligned structures reported previously and are analyzed to demonstrate that A is not preferentially incorporated opposite abasic lesions in eucaryotes.
Three-dimensional crystal structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor-groove-binding drug Hoechst 33258.
TLDR
The molecular structure of the DNA A-tract dodecamer d(CGCAAATTTGCG) complexed with the drug Hoechst 33258 has been determined by X-ray diffraction analysis and the structure is compared with other minor-groove-binding drug complexes.
...
...