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786-0

An adenocarcinoma cell line established from a 58 year old male patient with renal cell carcinoma.
National Institutes of Health

Papers overview

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2014
2014
Constructing a fluorescent probe for specific detection of cysteine over homocysteine and glutathione based on a novel cysteine-binding group but-3-yn-2-one.
A but-3-yn-2-one-based 7-diethylaminocoumarin dye was exploited as a fluorescent probe to specifically detect Cys over Hcy/GSH in… 
2013
2013
[Expressions of immunogenic molecules in low-dose radiotherapy-treated human renal clear cell carcinoma 786-0 cells].
OBJECTIVE To explore the effects of low-dose radiation on the expression of immunogenic membrane molecules calreticulin (CRT) and… 
2013
2013
ERK 5 / BMK 1 Is a Novel Target of the Tumor Suppressor VHL : Implication in Clear Cell Renal Carcinoma
Extracellular signal–regulated kinase 5 (ERK5), also known as big mitogen-activated protein kinase (MAPK) 1, is implicated in a… 
2011
2011
Calcineurin Inhibitor-Induced and Ras-Mediated Overexpression of VEGF in Renal Cancer Cells Involves mTOR through the Regulation of PRAS40
Malignancy is a major problem in patients treated with immunosuppressive agents. We have demonstrated that treatment with… 
2004
2004
Effect of Radiation and Ibuprofen on Normoxic Renal Carcinoma Cells Overexpressing Hypoxia-Inducible Factors by Loss of von Hippel–Lindau Tumor Suppressor Gene Function
Purpose: Tumor hypoxia is a major limiting factor for radiation therapy. Hypoxia-inducible factors (HIFs) are overexpressed in… 
2003
2003
pVHL-independent ubiquitination of HIF1alpha and its stabilization by cobalt ion.
Recent studies have shown that hypoxia-inducible factor1alpha (HIF1alpha) is ubiquitinated by an E3-ligase complex containing von… 
Highly Cited
2000
Highly Cited
2000
Inhibition of metastatic renal cell carcinomas expressing somatostatin receptors by a targeted cytotoxic analogue of somatostatin AN-238.
The effectiveness of chemotherapy targeted to somatostatin (SST) receptors based on cytotoxic SST analogue AN-238, consisting of… 
1999
1999
The von Hippel-Lindau Tumor Suppressor Gene Product Promotes, but Is Not Essential for, NEDD8 Conjugation to Cullin-2*
We have previously shown that human cullin-2 (Cul-2) is covalently modified at Lys-689 by NEDD8 (Wada, H., Yeh, E. T. H., and… 
1998
1998
The primary in vitro anticancer activity of "half-mustard type" phenothiazines in NCI's revised anticancer screening paradigm.
Some new phenothiazines have been synthesized on the basis of previous studies. The anticancer activity of "half-mustard type… 
Highly Cited
1997
Highly Cited
1997
Potent antitumor activity of a novel nucleoside analogue, BCH-4556 (beta-L-dioxolane-cytidine), in human renal cell carcinoma xenograft tumor models.
Beta-L-Dioxolane-cytidine (BCH-4556) is a novel anticancer nucleoside analogue with a stereochemically unnatural beta-L… 
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