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7-xylosyl-10-deacetylpaclitaxel

 
National Institutes of Health

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Broader (1)

Paclitaxel
analogs & derivatives

Papers overview

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2015
2015
Functional and structural properties of a novel cellulosome-like multienzyme complex: efficient glycoside hydrolysis of water-insoluble 7-xylosyl-10-deacetylpaclitaxel
Cellulosome is a kind of multienzyme complex that displays high activity, selectivity, and stability. Here, we report a novel… Expand
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2015
2015
Enzymatic hydrolysis of 7-xylosyltaxanes by an extracellular xylosidase from Cellulosimicrobium cellulans
ObjectivesTo find extracellular biocatalysts that can specifically and efficiently remove the C-7 xylosyl group from 7… Expand
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2012
2012
[Industrial preparative chromatography purification of 10-deacetylpaclitaxel, the enzymatic product of 7-xylosyl-10-deacetylpaclitaxel].
A scheme for industrial preparative chromatography purification of 10-deacetylpaclitaxel (10-DAP), the semi-synthesized precursor… Expand
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2011
2011
Involvement of mitochondrial permeability transition pore opening in 7-xylosyl-10-deacetylpaclitaxel-induced apoptosis.
7-Xylosyl-10-deacetylpaclitaxel is a natural hydrophilic paclitaxel derivative. It has long been used in Chinese clinics to treat… Expand
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2010
2010
Transport of a hydrophilic paclitaxel derivative, 7-xylosyl-10-deacetylpaclitaxel, by human intestinal epithelial Caco-2 cells.
7-Xylosyl-10-deacetylpaclitaxel is an active compound used in traditional Chinese medicine to treat cancer. However… Expand
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2010
2010
Optimization of Extration of 7-xylosyl-10-deacetylpaclitaxel from Taxus cuspidata
In an effort to search for natural products from Taxus cuspidata with improved pharmacological features compared to paclitaxel,7… Expand
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2010
2010
Optimization of extration of 7-xylosyl-10-deacetylpaclitaxel from Taxus cuspidata.
 
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2009
2009
Determination of a hydrophilic paclitaxel derivative, 7-xylosyl-10-deacetylpaclitaxel in rat plasma by LC-MS/MS.
A LC-MS/MS method for the determination of a hydrophilic paclitaxel derivative 7-xylosyl-10-deacetylpaclitaxel in rat plasma was… Expand
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2008
2008
Activation of the mitochondria-driven pathway of apoptosis in human PC-3 prostate cancer cells by a novel hydrophilic paclitaxel derivative, 7-xylosyl-10-deacetylpaclitaxel.
Paclitaxel, a natural product originally isolated from Taxus brevifolia, belongs to the most successful anticancer drugs… Expand
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2008
2008
Bacterial diversity of Taxus rhizosphere: culture-independent and culture-dependent approaches.
The regional variability of Taxus rhizosphere bacterial community composition and diversity was studied by comparative analysis… Expand
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