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7-methylguanosine triphosphate

Known as: 7-methyl-GTP, 2-amino-6,9-dihydro-9-(5-O-(hydroxy((hydroxy(phosphonooxy)phosphinyl)oxy)phosphinyl)-beta-D-ribofuranosyl)-7-methyl-6-oxo-1H-purinium, hydroxide, inner salt, m7-GTP 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

RNA Cap Analogs

Papers overview

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Highly Cited
2014
Highly Cited
2014
Preclinical Activity of VX-787, a First-in-Class, Orally Bioavailable Inhibitor of the Influenza Virus Polymerase PB2 Subunit
ABSTRACT VX-787 is a novel inhibitor of influenza virus replication that blocks the PB2 cap-snatching activity of the influenza… 
Highly Cited
2013
Highly Cited
2013
The DEAD-box helicase DDX3 substitutes for the cap-binding protein eIF4E to promote compartmentalized translation initiation of the HIV-1 genomic RNA
Here, we show a novel molecular mechanism promoted by the DEAD-box RNA helicase DDX3 for translation of the HIV-1 genomic RNA… 
Highly Cited
2006
Highly Cited
2006
Binding Specificities and Potential Roles of Isoforms of Eukaryotic Initiation Factor 4E in Leishmania
ABSTRACT The 5′ cap structure of trypanosomatid mRNAs, denoted cap 4, is a complex structure that contains unusual modifications… 
Highly Cited
2003
Highly Cited
2003
Structural features of human initiation factor 4E, studied by X-ray crystal analyses and molecular dynamics simulations.
Highly Cited
2002
Highly Cited
2002
Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5' cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins.
Highly Cited
2002
Highly Cited
2002
Crystal structures of 7-methylguanosine 5'-triphosphate (m(7)GTP)- and P(1)-7-methylguanosine-P(3)-adenosine-5',5'-triphosphate (m(7)GpppA)-bound human full-length eukaryotic initiation factor 4E…
The crystal structures of the full-length human eukaryotic initiation factor (eIF) 4E complexed with two mRNA cap analogues [7… 
Highly Cited
2001
Highly Cited
2001
Virus-Specific mRNA Capping Enzyme Encoded by Hepatitis E Virus
ABSTRACT Hepatitis E virus (HEV), a positive-strand RNA virus, is an important causative agent of waterborne hepatitis… 
Highly Cited
2000
Highly Cited
2000
Complex Formation between Potyvirus VPg and Translation Eukaryotic Initiation Factor 4E Correlates with Virus Infectivity
ABSTRACT The interaction between the viral protein linked to the genome (VPg) of turnip mosaic potyvirus (TuMV) and the… 
Highly Cited
2000
Highly Cited
2000
Cap‐dependent deadenylation of mRNA
Poly(A) tail removal is often the initial and rate‐limiting step in mRNA decay and is also responsible for translational… 
Highly Cited
1990
Highly Cited
1990
Alteration of the major phosphorylation site of eukaryotic protein synthesis initiation factor 4E prevents its association with the 48 S initiation complex.
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