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7-methylguanosine 5'-diphosphate

Known as: 7-methyl-GDP, 7-methylguanosine diphosphate, m(7)GDP 
National Institutes of Health

Related topics

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2 relations

Broader (1)

Guanosine Diphosphate
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
7-methylguanosine diphosphate (m(7)GDP) is not hydrolyzed but strongly bound by decapping scavenger (DcpS) enzymes and potently inhibits their activity.
Decapping scavenger (DcpS) enzymes catalyze the cleavage of a residual cap structure following 3' → 5' mRNA decay. Some previous… 
2009
2009
Initiation Factor eIF2-independent Mode of c-Src mRNA Translation Occurs via an Internal Ribosome Entry Site*
Overexpression and activation of the c-Src protein have been linked to the development of a wide variety of cancers. The… 
Highly Cited
2007
Highly Cited
2007
The Structure of Eukaryotic Translation Initiation Factor-4E from Wheat Reveals a Novel Disulfide Bond1[OA]
Eukaryotic translation initiation factor-4E (eIF4E) recognizes and binds the m7 guanosine nucleotide at the 5′ end of eukaryotic… 
2007
2007
Picornavirus Internal Ribosome Entry Site Elements Can Stimulate Translation of Upstream Genes*
Certain viral and cellular mRNAs initiate translation cap-independently at internal ribosome entry site (IRES) elements… 
Review
2006
Review
2006
Decapping the message: a beginning or an end.
Removal of the mRNA 5' cap is an important step in the regulation of mRNA stability. mRNAs are degraded by at least two distinct… 
2006
2006
Dcs2, a novel stress-induced modulator of m7GpppX pyrophosphatase activity that locates to P bodies.
2005
2005
Giardia lamblia RNA Cap Guanine-N2 Methyltransferase (Tgs2)*
Tgs1 is the enzyme responsible for converting 7-methylguanosine RNA caps to the 2,2,7-trimethylguanosine cap structures of small… 
2002
2002
Identification of mRNA decapping activities and an ARE-regulated 3' to 5' exonuclease activity in trypanosome extracts.
mRNA turnover is a regulated process that contributes to the steady state level of cytoplasmic mRNA. The amount of each mRNA… 
Highly Cited
2001
Highly Cited
2001
Virus-Specific mRNA Capping Enzyme Encoded by Hepatitis E Virus
ABSTRACT Hepatitis E virus (HEV), a positive-strand RNA virus, is an important causative agent of waterborne hepatitis… 
2000
2000
Structural requirements for the specific recognition of an m7G mRNA cap.
7-Methylguanosine (m(7)G), also known as the mRNA "cap", is used as a molecular tag in eukaryotic cells to mark the 5' end of… 
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