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7-methylguanosine 5'-diphosphate

Known as: 7-methyl-GDP, 7-methylguanosine diphosphate, m(7)GDP 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Guanosine Diphosphate
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
7-methylguanosine diphosphate (m(7)GDP) is not hydrolyzed but strongly bound by decapping scavenger (DcpS) enzymes and potently inhibits their activity.
Decapping scavenger (DcpS) enzymes catalyze the cleavage of a residual cap structure following 3' → 5' mRNA decay. Some previous… 
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2009
2009
Initiation Factor eIF2-independent Mode of c-Src mRNA Translation Occurs via an Internal Ribosome Entry Site*
  • H. Allam, N. Ali
  • The Journal of Biological Chemistry
  • 2009
  • Corpus ID: 25727516
Overexpression and activation of the c-Src protein have been linked to the development of a wide variety of cancers. The… 
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Highly Cited
2007
Highly Cited
2007
The Structure of Eukaryotic Translation Initiation Factor-4E from Wheat Reveals a Novel Disulfide Bond1[OA]
Eukaryotic translation initiation factor-4E (eIF4E) recognizes and binds the m7 guanosine nucleotide at the 5′ end of eukaryotic… 
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2007
2007
Picornavirus Internal Ribosome Entry Site Elements Can Stimulate Translation of Upstream Genes*
Certain viral and cellular mRNAs initiate translation cap-independently at internal ribosome entry site (IRES) elements… 
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2007
2007
After fertilization of sea urchin eggs, eIF4G is post-translationally modified and associated with the cap-binding protein eIF4E
Release of eukaryotic initiation factor 4E (eIF4E) from its translational repressor eIF4E-binding protein (4E-BP) is a crucial… 
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Review
2006
Review
2006
Decapping the message: a beginning or an end.
Removal of the mRNA 5' cap is an important step in the regulation of mRNA stability. mRNAs are degraded by at least two distinct… 
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2006
2006
Dcs2, a novel stress-induced modulator of m7GpppX pyrophosphatase activity that locates to P bodies.
The eukaryotic "scavenger" type decapping enzyme, an m(7)GpppX pyrophosphatase, is active in cellular mRNA metabolism and thereby… 
2002
2002
Identification of mRNA decapping activities and an ARE-regulated 3' to 5' exonuclease activity in trypanosome extracts.
mRNA turnover is a regulated process that contributes to the steady state level of cytoplasmic mRNA. The amount of each mRNA… 
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Highly Cited
2001
Highly Cited
2001
Virus-Specific mRNA Capping Enzyme Encoded by Hepatitis E Virus
ABSTRACT Hepatitis E virus (HEV), a positive-strand RNA virus, is an important causative agent of waterborne hepatitis… 
2000
2000
Structural requirements for the specific recognition of an m7G mRNA cap.
7-Methylguanosine (m(7)G), also known as the mRNA "cap", is used as a molecular tag in eukaryotic cells to mark the 5' end of… 
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