Skip to search formSkip to main contentSkip to account menu

7-ethoxy-4-trifluoromethylcoumarin

Known as: 7-ethoxy-4-(trifluoromethyl)-2H-1-benzypyran-2-one, ETFC cpd 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Coumarins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Structure-Function Analysis of Mammalian CYP2B Enzymes Using 7-Substituted Coumarin Derivatives as Probes: Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic Metabolism
Crystal structures of CYP2B35 and CYP2B37 from the desert woodrat were solved in complex with 4-(4-chlorophenyl)imidazole (4-CPI… 
Review
2010
Review
2010
Cytochrome P450-mediated hepatic metabolism of new fluorescent substrates in cats and dogs.
This study aimed to investigate the biotransformation of cat liver microsomes in comparison to dogs and humans using a high… 
2008
2008
Identification and Analysis of Conserved Sequence Motifs in Cytochrome P450 Family 2
Using a multiple alignment of 175 cytochrome P450 (CYP) family 2 sequences, 20 conserved sequence motifs (CSMs) were identified… 
2006
2006
Investigation of the role of cytochrome P450 2B4 active site residues in substrate metabolism based on crystal structures of the ligand-bound enzyme.
2006
2006
Determination of CYP2B6 component of 7-ethoxy-4-trifluoromethylcoumarin O-deethylation activity in human liver microsomes.
The cytochrome P450 enzyme CYP2B6 plays an important role in the metabolism of structurally diverse drugs, including the… 
2005
2005
Functional role of residues in the helix B' region of cytochrome P450 2B1.
2005
2005
Expression and activity of CYP2E1 in circulating lymphocytes are not altered in diabetic individuals.
1999
1999
Metabolism of N-nitrosobenzylmethylamine by human cytochrome P-450 enzymes.
N-Nitrosobenzylmethylamine (NBzMA) is a potent esophageal carcinogen in rodents, and has been found as a dietary contaminant in… 
1998
1998
High-performance liquid chromatographic method for measurement of cytochrome P450-mediated metabolism of 7-ethoxy-4-trifluoromethylcoumarin.
1995
1995
Mechanistic studies of 9-ethynylphenanthrene-inactivated cytochrome P450 2B1.
The mechanism of inactivation of the major phenobarbital-inducible cytochrome P450 of rat liver, P450 2B1, by 9… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)