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7-ethoxy-4-trifluoromethylcoumarin

Known as: 7-ethoxy-4-(trifluoromethyl)-2H-1-benzypyran-2-one, ETFC cpd 
National Institutes of Health

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1 relation

Broader (1)

Coumarins

Papers overview

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2009
2009
Functional expression in Bacillus subtilis of mammalian NADPH-cytochrome P450 oxidoreductase and its spore-display.
Highly Cited
2005
Highly Cited
2005
Comparative acaricide susceptibility and detoxifying enzyme activities in field-collected resistant and susceptible strains of Tetranychus urticae.
A field-collected strain (MR-VL) of the two-spotted spider mite, Tetranychus urticae Koch, exhibited strong resistance to… 
Highly Cited
2004
Highly Cited
2004
Fluorescence-based assays for screening nine cytochrome P450 (P450) activities in intact cells expressing individual human P450 enzymes.
In this study we describe a battery of fluorescence assays for rapid measurement in intact cells of the activity of nine… 
Highly Cited
2003
Highly Cited
2003
Functional characterization of cytochrome P450 2B6 allelic variants.
Cytochrome P450 (P450) 2B6 is a hepatic enzyme of potential importance for the metabolism of clinically used drugs and… 
2002
2002
Mechanism-based inactivation of cytochromes P450 2E1 and 2E1 T303A by tert-butyl acetylenes: characterization of reactive intermediate adducts to the heme and apoprotein.
The kinetics for the inactivation of cytochrome P450 2E1 and the mutant P450 2E1 T303A by tert-butyl acetylene (tBA) and tert… 
2000
2000
Mechanism-based inactivation of cytochrome P450 2B1 by 7-ethynylcoumarin: verification of apo-P450 adduction by electrospray ion trap mass spectrometry.
7-Ethynylcoumarin was synthesized as a potential mechanism-based inhibitor, and it was found to be an effective inactivator of 7… 
Highly Cited
1999
Highly Cited
1999
Effect of methanol, ethanol, dimethyl sulfoxide, and acetonitrile on in vitro activities of cDNA-expressed human cytochromes P-450.
The effects of methanol, ethanol, dimethyl sulfoxide (DMSO), and acetonitrile were studied in vitro on nine individual… 
1999
1999
Inactivation of cytochrome P450 2E1 by benzyl isothiocyanate.
The cytochrome P450 enzymes constitute a family of phase I enzymes that play a prominent role in the metabolism of a great… 
Highly Cited
1997
Highly Cited
1997
Human cytochrome P4502B6: interindividual hepatic expression, substrate specificity, and role in procarcinogen activation.
The level of expression and interindividual variation in human hepatic microsomal cytochrome P450 (CYP) 2B6 was characterized… 
Highly Cited
1988
Highly Cited
1988
A direct, highly sensitive assay for cytochrome P-450 catalyzed O-deethylation using a novel coumarin analog.
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