Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 227,741,294 papers from all fields of science
Search
Sign In
Create Free Account
7-ethoxy-4-trifluoromethylcoumarin
Known as:
7-ethoxy-4-(trifluoromethyl)-2H-1-benzypyran-2-one
, ETFC cpd
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
1 relation
Broader (1)
Coumarins
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Structure-Function Analysis of Mammalian CYP2B Enzymes Using 7-Substituted Coumarin Derivatives as Probes: Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic Metabolism
M. Shah
,
Jingbao Liu
,
+6 authors
J. Halpert
Molecular Pharmacology
2016
Corpus ID: 11189355
Crystal structures of CYP2B35 and CYP2B37 from the desert woodrat were solved in complex with 4-(4-chlorophenyl)imidazole (4-CPI…
Expand
Review
2010
Review
2010
Cytochrome P450-mediated hepatic metabolism of new fluorescent substrates in cats and dogs.
C. D. van Beusekom
,
L. Schipper
,
J. Fink-Gremmels
Journal of Veterinary Pharmacology and…
2010
Corpus ID: 33013309
This study aimed to investigate the biotransformation of cat liver microsomes in comparison to dogs and humans using a high…
Expand
2008
2008
Identification and Analysis of Conserved Sequence Motifs in Cytochrome P450 Family 2
N. Oezguen
,
Santosh Kumar
,
A. Hindupur
,
W. Braun
,
B. K. Muralidhara
,
J. Halpert
Journal of Biological Chemistry
2008
Corpus ID: 25916152
Using a multiple alignment of 175 cytochrome P450 (CYP) family 2 sequences, 20 conserved sequence motifs (CSMs) were identified…
Expand
2006
2006
Investigation of the role of cytochrome P450 2B4 active site residues in substrate metabolism based on crystal structures of the ligand-bound enzyme.
C. Hernandez
,
Santosh Kumar
,
Hong Liu
,
J. Halpert
Archives of Biochemistry and Biophysics
2006
Corpus ID: 41458153
2006
2006
Determination of CYP2B6 component of 7-ethoxy-4-trifluoromethylcoumarin O-deethylation activity in human liver microsomes.
Thomas K. H. Chang
,
C. Crespi
,
D. Waxman
Methods in molecular biology
2006
Corpus ID: 25577652
The cytochrome P450 enzyme CYP2B6 plays an important role in the metabolism of structurally diverse drugs, including the…
Expand
2005
2005
Functional role of residues in the helix B' region of cytochrome P450 2B1.
Wataru Honma
,
Weihua Li
,
Hong Liu
,
E. Scott
,
J. Halpert
Archives of Biochemistry and Biophysics
2005
Corpus ID: 7283419
2005
2005
Expression and activity of CYP2E1 in circulating lymphocytes are not altered in diabetic individuals.
L. Pucci
,
V. Chirulli
,
+5 authors
V. Longo
Pharmacological Research
2005
Corpus ID: 25323281
1999
1999
Metabolism of N-nitrosobenzylmethylamine by human cytochrome P-450 enzymes.
M. Morse
,
Jerry Lu
,
G. Stoner
,
S. Murphy
,
L. Peterson
Journal of Toxicology and Environmental Health…
1999
Corpus ID: 7957780
N-Nitrosobenzylmethylamine (NBzMA) is a potent esophageal carcinogen in rodents, and has been found as a dietary contaminant in…
Expand
1998
1998
High-performance liquid chromatographic method for measurement of cytochrome P450-mediated metabolism of 7-ethoxy-4-trifluoromethylcoumarin.
Mark A. Morse
,
Jerry Lu
Journal of Chromatography B: Biomedical Sciences…
1998
Corpus ID: 13083385
1995
1995
Mechanistic studies of 9-ethynylphenanthrene-inactivated cytochrome P450 2B1.
E. S. Roberts
,
E. S. Roberts
,
+4 authors
P. Hollenberg
Archives of Biochemistry and Biophysics
1995
Corpus ID: 22474296
The mechanism of inactivation of the major phenobarbital-inducible cytochrome P450 of rat liver, P450 2B1, by 9…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE