7-(2-hydroxypropyl)guanine

Known as: 7-HPG 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1972-2003
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Papers overview

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2003
2003
Propylene oxide (PO) is a high-volume chemical intermediate that causes a low incidence of nasal tumors in rodents exposed to… (More)
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2003
2003
Ethylene oxide (EO) and propylene oxide (PO) are direct acting mutagens with high Swain-Scott s-values, which indicate that they… (More)
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2003
2003
The main purpose of the study was to establish the relation between exposure dose of propylene oxide (PO) and dose in various… (More)
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2000
2000
Propylene oxide (PO) is a relatively weak mutagen that induces nasal tumor formation in rats during long-term inhalation studies… (More)
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1999
1999
Propylene oxide, a widely used monofunctional alkylating agent, has been shown to be genotoxic in in vitro test systems and… (More)
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1998
1998
7-(2-Hydroxypropyl)guanine (7-HPG) constitutes the major adduct from alkylation of DNA by the genotoxic carcinogen, propylene… (More)
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Review
1997
Review
1997
The results from mutagenic and carcinogenic studies of propylene oxide (PO) and the current efforts to develop molecular… (More)
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1972
1972
1. Propylene oxide reacts with DNA in aqueous buffer solution at about neutral pH to yield two principal products, identified as… (More)
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