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6-lactoyltetrahydropterin

Known as: 1'-oxo-2'-hydroxypropyl-tetrahydropterin, lactoyl-H4-pterin, lactoyl-PH4 
National Institutes of Health

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2 relations

Broader (1)

Biopterin
analogs & derivatives

Papers overview

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2011
2011
Pseudoexon exclusion by antisense therapy in 6‐pyruvoyl‐tetrahydropterin synthase deficiency
Antisense oligonucleotide therapy to modulate splicing mutations in inherited diseases is emerging as a treatment option also for… 
2003
2003
Tetrahydrobiopterin is synthesized from 6-pyruvoyl-tetrahydropterin by the human aldo-keto reductase AKR1 family members.
1993
1993
Hyperphenylalaninemia and pterin metabolism in serum and erythrocytes.
1991
1991
Purification and cDNA cloning of rat 6-pyruvoyl-tetrahydropterin synthase.
1989
1989
The biosynthesis of tetrahydrobiopterin in rat brain. Purification and characterization of 6-pyruvoyl tetrahydropterin (2'-oxo)reductase.
An enzyme with 6-pyruvoyl tetrahydropterin (6PPH4) (2'-oxo)reductase activity was purified to near homogeneity from whole rat… 
1989
1989
Human liver 6-pyruvoyl tetrahydropterin reductase is biochemically and immunologically indistinguishable from aldose reductase.
Highly Cited
1986
Highly Cited
1986
Biosynthesis of tetrahydrobiopterin. Purification and characterization of 6-pyruvoyl-tetrahydropterin synthase from human liver.
6-Pyruvoyl-tetrahydropterin synthase, which catalyzes the first step in the conversion of 7,8-dihydroneopterin triphosphate to… 
1986
1986
Prenatal diagnosis of “dihydrobiopterin synthetase” deficiency, a variant form of phenylketonuria
Amniocentesis was performed at 19 weeks gestation in a mother who had previously delivered a boy with “dihydrobiopterin… 
1985
1985
Biosynthesis of tetrahydrobiopterin: conversion of dihydroneopterin triphosphate to tetrahydropterin intermediates.
Highly Cited
1976
Highly Cited
1976
Phospholipid-induced activation of tyrosine hydroxylase from rat brain striatal synaptosomes.
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