6-deoxyerythronolide B

Known as: 3,5,11-trihydroxyerythranolid-9-one, Erythronolide A, 6,12-dideoxy- 
 
National Institutes of Health

Papers overview

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2008
2008
Chromosomal engineering was used to localize the deoxyerythronolide B synthase (DEBS) genes and propionyl-CoA carboxylase (PCC… (More)
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2007
2007
6-Deoxyerythronolide B synthase (DEBS) is a modular polyketide synthase (PKS) responsible for the biosynthesis of 6-dEB (1), the… (More)
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Review
2007
Review
2007
6-Deoxyerythronolide B, the macrocyclic aglycone of the antibiotic erythromycin, is synthesized by a polyketide synthase (PKS… (More)
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2007
2007
We report the 2.6 A X-ray crystal structure of a 190 kDa homodimeric fragment from module 3 of the 6-deoxyerthronolide B synthase… (More)
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2006
2006
[reaction: see text] The enantioselective synthesis of the carbon skeleton of 6-deoxyerythronolide B has been achieved in 23… (More)
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2006
2006
The x-ray crystal structure of a 194-kDa fragment from module 5 of the 6-deoxyerythronolide B synthase has been solved at 2.7… (More)
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2006
2006
The x-ray crystal structure of a 194-kDa fragment from module 5 of the 6-deoxyerythronolide B synthase has been solved at 2.7… (More)
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2005
2005
Chemobiosynthesis (J. R. Jacobsen, C. R. Hutchinson, D. E. Cane, and C. Khosla, Science 277:367-369, 1997) is an important route… (More)
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2003
2003
Escherichia coli is an attractive candidate as a host for polyketide production and has been engineered to produce the… (More)
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Highly Cited
2001
Highly Cited
2001
The macrocyclic core of the antibiotic erythromycin, 6-deoxyerythronolide B (6dEB), is a complex natural product synthesized by… (More)
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