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6-chlorotacrine

Known as: 6-Cl-tacrine 
 
National Institutes of Health

Papers overview

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2018
2018
BACKGROUND 6-chlorotacrine is a cholinesterase inhibitor showing good inhibitory potential, even better than parent compound… Expand
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2017
2017
A novel series of 6-chlorotacrine-scutellarin hybrids was designed, synthesized and the biological activity as potential anti… Expand
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2014
2014
Optimization of an essentially inactive 3,4-dihydro-2H-pyrano[3,2-c]quinoline carboxylic ester derivative as acetylcholinesterase… Expand
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2013
2013
The number of people suffering from Alzheimer's disease (AD) is expected to increase dramatically in the coming decades… Expand
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2010
2010
Two novel families of dual binding site acetylcholinesterase (AChE) inhibitors have been developed, consisting of a tacrine or 6… Expand
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Highly Cited
2009
Highly Cited
2009
Two isomeric series of dual binding site acetylcholinesterase (AChE) inhibitors have been designed, synthesized, and tested for… Expand
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Highly Cited
2008
Highly Cited
2008
A novel series of donepezil-tacrine hybrids designed to simultaneously interact with the active, peripheral and midgorge binding… Expand
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Highly Cited
2005
Highly Cited
2005
A new series of donepezil-tacrine hybrid related derivatives have been synthesised as dual acetylcholinesterase inhibitors that… Expand
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1996
1996
Multiconfiguration thermodynamic integration was used to determine the relative binding strength of tacrine and 6-chlorotacrine… Expand
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1996
1996
Multiconfiguration thermodynamic integration was used to determine the relative binding strength of tacrine and 6-chlorotacrine… Expand
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