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6-chlorotacrine

Known as: 6-Cl-tacrine 
National Institutes of Health

Papers overview

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2019
2019
A novel molecule 2 formed by combining 6-chlorotacrine (6-Cl-THA) and memantine proved to be a promising multipotent hybrid… 
2017
2017
BACKGROUND 6-chlorotacrine is a cholinesterase inhibitor showing good inhibitory potential, even better than parent compound… 
2013
2013
The number of people suffering from Alzheimer's disease (AD) is expected to increase dramatically in the coming decades… 
Highly Cited
2009
Highly Cited
2009
Two isomeric series of dual binding site acetylcholinesterase (AChE) inhibitors have been designed, synthesized, and tested for… 
Highly Cited
2008
Highly Cited
2008
A novel series of donepezil-tacrine hybrids designed to simultaneously interact with the active, peripheral and midgorge binding… 
Highly Cited
2005
Highly Cited
2005
1996
1996
Multiconfiguration thermodynamic integration was used to determine the relative binding strength of tacrine and 6-chlorotacrine…