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6-chlorotacrine

Known as: 6-Cl-tacrine 
 
National Institutes of Health

Papers overview

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2018
2018
BACKGROUND 6-chlorotacrine is a cholinesterase inhibitor showing good inhibitory potential, even better than parent compound… Expand
2017
2017
A novel series of 6-chlorotacrine-scutellarin hybrids was designed, synthesized and the biological activity as potential anti… Expand
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2014
2014
Optimization of an essentially inactive 3,4-dihydro-2H-pyrano[3,2-c]quinoline carboxylic ester derivative as acetylcholinesterase… Expand
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2013
2013
The number of people suffering from Alzheimer's disease (AD) is expected to increase dramatically in the coming decades… Expand
Highly Cited
2010
Highly Cited
2010
Two novel families of dual binding site acetylcholinesterase (AChE) inhibitors have been developed, consisting of a tacrine or 6… Expand
Highly Cited
2009
Highly Cited
2009
Two isomeric series of dual binding site acetylcholinesterase (AChE) inhibitors have been designed, synthesized, and tested for… Expand
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Highly Cited
2008
Highly Cited
2008
A novel series of donepezil-tacrine hybrids designed to simultaneously interact with the active, peripheral and midgorge binding… Expand
Highly Cited
2005
Highly Cited
2005
A new series of donepezil-tacrine hybrid related derivatives have been synthesised as dual acetylcholinesterase inhibitors that… Expand
1996
1996
Multiconfiguration thermodynamic integration was used to determine the relative binding strength of tacrine and 6-chlorotacrine… Expand
1996
1996
Multiconfiguration thermodynamic integration was used to determine the relative binding strength of tacrine and 6-chlorotacrine… Expand