6-Aminonicotinamide

Known as: 6-Aminonicotinamide [Chemical/Ingredient], 6-AN, 6 Aminonicotinamide 
A synthetic analogue and nicotinamide antagonist with cytotoxic properties, 6-Aminonicotinamide forms an abnormal NAD (ubiquitous metabolic pathway… (More)
National Institutes of Health

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2014
2014
UNLABELLED The mammalian target of rapamycin complex 1 (mTORC1) is hyperactive in many human cancers and in tuberous sclerosis… (More)
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Highly Cited
2009
Highly Cited
2009
Increased oxidative stress is a known cause of cardiac dysfunction in animals and patients with diabetes, but the sources of… (More)
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Highly Cited
2006
Highly Cited
2006
In the failing heart, NADPH oxidase and uncoupled NO synthase utilize cytosolic NADPH to form superoxide. NADPH is supplied… (More)
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2005
2005
The aim was to exploit simultaneous inhibition of glycolytic and pentose phosphate pathways of energy production for… (More)
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2003
2003
6-aminonicotinamide (6-AN) is a niacin antagonist, which leads to degeneration of gray matter astrocytes mainly in the brainstem… (More)
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2002
2002
6-Aminonicotinamide (6-AN) is a niacin antagonist, which leads to degeneration of gray matter astrocytes. Metallothionein 1+2 (MT… (More)
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1999
1999
The pyridine nucleotide 6-aminonicotinamide (6AN) was shown recently to sensitize a number of human tumor cell lines to cisplatin… (More)
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1998
1998
The nicotinamide analogue 6-aminonicotinamide (6AN) is presently undergoing evaluation as a potential modulator of the action of… (More)
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1997
1997
The cerebral distribution of metallothioneins I and II (MT-I + II) was studied in adult rats subjected to i.p. injection with the… (More)
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1975
1975
Focal areas of primary demyelination were produced in the spinal cords of rats by means of local injections of 6… (More)
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