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589C80
National Institutes of Health
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1 relation
Broader (1)
tucaresol
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1993
1993
The pharmacokinetics, tolerability and pharmacodynamics of tucaresol (589C80; 4[2-formyl-3-hydroxyphenoxymethyl] benzoic acid), a potential anti-sickling agent, following oral administration to…
Paul Edward Rolan
,
Joanne E Parker
,
+5 authors
John Jacob Posner
British journal of clinical pharmacology
1993
1. Tucaresol (589C80; 4[2-formyl-3-hydroxyphenoxymethyl] benzoic acid) interacts stoichiometrically with haemoglobin to increase…
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1992
1992
Substituted benzaldehydes (12C79 and 589C80) that stabilize oxyhaemoglobin also protect sickle cells against calcium-mediated dehydration.
Philip C W Stone
,
Gerard B Nash
,
Jennifer Stuart
British journal of haematology
1992
Reversibly sickled cells from patients with homozygous sickle-cell disease were prepared by Percoll-Isopaque density gradient…
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