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566C80

Known as: 566C80 hydroxynaphthoquinone, hydroxynaphthoquinone 566C80, hydroxynaphthoquinone, 566C80 
National Institutes of Health

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Highly Cited
1998
Highly Cited
1998
Atovaquone (Mepron, 566c80) is an effective agent against Pneumocystis carinii, which probably acts by binding to cytochrome b… Expand
Highly Cited
1993
Highly Cited
1993
BACKGROUND Both trimethoprim-sulfamethoxazole and pentamidine are effective as treatments for Pneumocystis carinii pneumonia, but… Expand
Highly Cited
1993
Highly Cited
1993
The activity of atovaquone in the treatment of murine toxoplasmosis was greatly enhanced when administered in combination with… Expand
Highly Cited
1992
Highly Cited
1992
The site of action of the antimalarial compound 2-[trans-4-(4'-chlorophenyl) cyclohexyl]-3-hydroxy-1,4-naphthoquinone (566C80… Expand
Highly Cited
1992
Highly Cited
1992
The in vitro and in vivo activities of the hydroxynaphthoquinone 566C80 against the cyst form of Toxoplasma gondii were evaluated… Expand
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Highly Cited
1991
Highly Cited
1991
566C80 is a novel hydroxynaphthoquinone with broad-spectrum anti-parasitic properties. In vitro the compound was more potent… Expand
Highly Cited
1991
Highly Cited
1991
Compound 566C80, 2-[trans-4-(4-chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthoquinone, was studied for its in vitro and in vivo… Expand
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Highly Cited
1991
Highly Cited
1991
BACKGROUND The drug 566C80 is an investigational hydroxynaphthoquinone that is active against Pneumocystis carinii in vitro and… Expand
Highly Cited
1990
Highly Cited
1990
The efficacy of a new class of drugs for Pneumocystis carinii pneumonitis was demonstrated. 566C80, a hydroxynaphthoquinone… Expand
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Highly Cited
1985
Highly Cited
1985
A series of hydroxynaphthoquinones, all derivatives of the antitheilerial hydroxynaphthoquinone parvaquone (993C, Clexon… Expand