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5-methyltetrahydrohomofolate

Known as: Emofolin Sodium, MeTHHF Disodium, Methyltetrahydrohomofolate 
The sodium salt of a synthetic antimetabolite analogue of folate with antineoplastic activity. Emfolin sodium competes for the folate binding site of… 
National Institutes of Health

Papers overview

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Review
2004
Review
2004
5-methyltetrahydrohomofolate
Abstract5-methyltetrahydrohomofolate was developed in the 1970's as an antifolate with the potential to overcome methotrexate… 
1987
1987
Carrier-mediated transport of folate compounds in L1210 cells. Initial rate kinetics and extent of duality of entry routes for folic acid and diastereomers of 5-methyltetrahydrohomofolate in the…
1983
1983
Clinical pharmacokinetics of 5-methyltetrahydrohomofolate.
DL-N5-Methyltetrahydrohomofolate (MTHHF; NSC-139490; N- [(4-[(2-(2-amino-3,4,5,6,7,8-hexahydro-4-oxo-5-methyl-6- pteridinyl)ethyl… 
1982
1982
5-Methyltetrahydrohomofolate (MTHHF): Phase I trial and pharmacology in man
1981
1981
Disposition of 5-methyltetrahydrohomofolate and methotrexate in rats.
: The pharmacologic disposition of [methyl-14C]5-methyltetrahydrohomofolate (MTHHF) and [3H]methotrexate (MTX) has been studied… 
1981
1981
Disposition of 5-methyltetrahydrohomofolate and methotrexate in rats.
The pharmacologic disposition of [methyl-14C]5-methyltetrahydrohomofolate (MTHHF) and [3H]methotrexate (MTX) has been studied in… 
1981
1981
Clinical pharmacologic studies of 5-methyltetrahydrohomofolate (MTHHF, NSC 139490)
1979
1979
Disposition of 5-methyltetrahydrohomofolate in mice, dogs, and monkeys.
The pharmacologic disposition of [methyl-14C]5-methyltetrahydrohomofolate (MTHHF) has been studied in mice, dogs, and monkeys… 
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