5-methylpyrazole-3-carboxylic acid

Kynurenic acid (KYNA), an astrocyte-derived, endogenous antagonist of α7 nicotinic acetylcholine and excitatory amino acid… Expand

We studied the hypothesis that spinal d-amino acid oxidase (DAAO) that is expressed in astrocytes and that has been reported to… Expand

We have found that mutation of D-amino acid oxidase (DAO) diminished formalin-induced tonic pain. The present research further… Expand

L-Kynurenine (KYN), a tryptophan metabolite, is metabolized to kynurenic acid (KYNA), which is an antagonist of N-methyl-D… Expand

We studied by radioimmunoassay the plasma levels of 13,14-dihydro-15-keto-prostaglandin (PG)E 2 (the stable metabolite of PGE 2… Expand

Because the presence of an elevated plasma free fatty acid (FFA) concentration is not always sufficient to promote ketogenesis… Expand

Abstract The antilipemic effects of nicotinic acid (NA) and 3-methylpyrazole-5-carboxylic acid (MPC) were compared in vivo and in… Expand

5-Methylpyrazole-3-carboxylic acid is completely absorbed and rapidly excreted in the rat, dog, and human. After 1- or 9-mg./Kg… Expand

5-Methylpyrazole-3-carboxylic acid stimulated the incorporation of labeled glucose into adipose tissue in vivo without… Expand

As a hypoglycemic agent, 5-methylpyrazole-3-carboxylic acid was found to be 116 times more potent orally than tolbutamide in… Expand