5-methylpyrazole-3-carboxylic acid

Because the presence of an elevated plasma free fatty acid (FFA) concentration is not always sufficient to promote ketogenesis… Expand

Inhibition of epinephrine-stimulated lipolysis in vitro by U-19425 and nicotinic acid at concentrations of 10 -6 , 10 -5 and 10… Expand

Abstract The antilipemic effects of nicotinic acid (NA) and 3-methylpyrazole-5-carboxylic acid (MPC) were compared in vivo and in… Expand

5-Methylpyrazole-3-carboxylic acid is completely absorbed and rapidly excreted in the rat, dog, and human. After 1- or 9-mg./Kg… Expand

5-Methylpyrazole-3-carboxylic acid stimulated the incorporation of labeled glucose into adipose tissue in vivo without… Expand

5-Methylpyrazole-3-carboxylic acid in concentrations between 10-8 and 10-6 M inhibited the glycerol release of adipose tissue of… Expand

Summary After 4 days of treatment with U-19425, rats no longer respond to the drug with a decrease in plasma FFA and blood sugar… Expand

Abstract 1. 1. Both lipolytic hormones (ACTH, epinephrine, glucagon) and ouabain were found to stimulate the uptake of glucose… Expand

As a hypoglycemic agent, 5-methylpyrazole-3-carboxylic acid was found to be 116 times more potent orally than tolbutamide in… Expand