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5-methylpyrazole-3-carboxylic acid
Known as:
3-methylpyrazole-5-carboxylic acid
National Institutes of Health
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Related topics
Related topics
2 relations
Narrower (1)
AS 057278
Broader (1)
Pyrazoles
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1979
1979
Correction of Ketosis by Suppression of Lipolysis with 5-Methylpyrazole-3-Carboxylic Acid in Rats with Established Diabetic Ketoacidosis
L. Axelrod
,
P. Lloyd-Jones
,
D. Martin
Diabetes
1979
Corpus ID: 44453651
Because the presence of an elevated plasma free fatty acid (FFA) concentration is not always sufficient to promote ketogenesis…
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1968
1968
Effects of 5-methylpyrazole-3-carboxylic acid (U-19425) and nicotinic acid on lipolysis in vitro and in vivo and on cyclic-3',5'-AMP phosphodiesterase.
F. P. Kupiecki
,
N. Marshall
The Journal of pharmacology and experimental…
1968
Corpus ID: 28313271
Inhibition of epinephrine-stimulated lipolysis in vitro by U-19425 and nicotinic acid at concentrations of 10 -6 , 10 -5 and 10…
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1968
1968
Comparison of the antilipemic effect of nicotinic acid (NA) and 3-methylpyrazole-5-carboxylic acid (MPC) in rats.
G. Tamasi
,
J. Borsy
,
A. Patthy
Biochemical pharmacology
1968
Corpus ID: 28454245
Abstract The antilipemic effects of nicotinic acid (NA) and 3-methylpyrazole-5-carboxylic acid (MPC) were compared in vivo and in…
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1967
1967
Absorption, metabolism, and excretion of 5-methylpyrazole-3-carboxylic acid in the rat, dog, and human.
D. L. Smith
,
J. Wagner
,
G. Gerritsen
Journal of pharmaceutical sciences
1967
Corpus ID: 20782988
5-Methylpyrazole-3-carboxylic acid is completely absorbed and rapidly excreted in the rat, dog, and human. After 1- or 9-mg./Kg…
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1967
1967
Effects of 5-methylpyrazole-3-carboxylic acid on adipose tissue. II. Antilipolytic and hypoglycemic effects in vivo.
E. Froesch
,
M. Waldvogel
,
U. Meyer
,
A. Jakob
,
A. Labhart
Molecular pharmacology
1967
Corpus ID: 40215540
5-Methylpyrazole-3-carboxylic acid stimulated the incorporation of labeled glucose into adipose tissue in vivo without…
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1967
1967
Effects of 5-methylpyrazole-3-carboxylic acid on adipose tissue. I. Inhibition of lipolysis, effects on glucose, fructose, and glycogen metabolism in vitro and comparison with insulin.
E. Froesch
,
M. Waldvogel
,
U. Meyer
,
A. Jakob
,
A. Labhart
Molecular pharmacology
1967
Corpus ID: 31477391
5-Methylpyrazole-3-carboxylic acid in concentrations between 10-8 and 10-6 M inhibited the glycerol release of adipose tissue of…
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1967
1967
Development of Tachyphylaxis to the Antilipolytic, Hypoglycemic Agent, 5-Methylpyrazole-3-carboxylic Acid, U-19425.∗
G. Gerritsen
,
W. Dulin
Proceedings of the Society for Experimental…
1967
Corpus ID: 41047975
Summary After 4 days of treatment with U-19425, rats no longer respond to the drug with a decrease in plasma FFA and blood sugar…
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Highly Cited
1967
Highly Cited
1967
Insulin-like action of ouabain. I. Effect on carbohydrate metabolism.
R. Ho
,
B. Jeanrenaud
Biochimica et biophysica acta
1967
Corpus ID: 27234974
Abstract 1. 1. Both lipolytic hormones (ACTH, epinephrine, glucagon) and ouabain were found to stimulate the uptake of glucose…
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Highly Cited
1965
Highly Cited
1965
The effect of 5-methylpyrazole-3-carboxylic acid on carbohydrate and free fatty acid metabolism.
G. Gerritsen
,
W. Dulin
The Journal of pharmacology and experimental…
1965
Corpus ID: 36116318
As a hypoglycemic agent, 5-methylpyrazole-3-carboxylic acid was found to be 116 times more potent orally than tolbutamide in…
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1965
1965
5-METHYLPYRAZOLE-3-CARBOXYLIC ACID. THE POTENT HYPOGLYCEMIC METABOLITE OF 3,5-DIMETHYLPYRAZOLE IN THE RAT.
D. L. Smith
,
A. A. Forist
,
W. Dulin
Journal of medicinal chemistry
1965
Corpus ID: 20271223
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