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5-hydroxyuracil

Known as: 2,4,5(3H)-Pyrimidinetrione, dihydro- 
National Institutes of Health

Related topics

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2 relations

Broader (1)

Uracil
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Base excision repair of oxidative DNA damage and association with cancer and aging.
Aging has been associated with damage accumulation in the genome and with increased cancer incidence. Reactive oxygen species… 
Review
2007
Review
2007
Uracil in DNA--general mutagen, but normal intermediate in acquired immunity.
Review
2007
Review
2007
Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease
Increasing evidence supports a role for oxidative DNA damage in aging and several neurodegenerative diseases including Alzheimer… 
Highly Cited
2006
Highly Cited
2006
NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells.
Review
2002
Review
2002
Biological consequences of free radical-damaged DNA bases.
  • S. Wallace
  • Free Radical Biology & Medicine
  • 2002
  • Corpus ID: 11852794
Review
2002
Review
2002
Repair of deaminated bases in DNA.
  • Y. Kow
  • Free Radical Biology & Medicine
  • 2002
  • Corpus ID: 22967970
Highly Cited
1998
Highly Cited
1998
Increased Nuclear DNA Oxidation in the Brain in Alzheimer's Disease
Abstract: Multiple lines of evidence indicate that oxidative stress is a contributor to neuronal death in Alzheimer's disease (AD… 
Highly Cited
1998
Highly Cited
1998
Oxidized, deaminated cytosines are a source of C --> T transitions in vivo.
The most common base substitution arising from oxidative damage of DNA is a GC --> AT transition. In an effort to determine the… 
Highly Cited
1997
Highly Cited
1997
An Assessment of Oxidative Damage to Proteins, Lipids, and DNA in Brain from Patients with Alzheimer's Disease
Abstract: Oxidative stress may contribute to neuronal loss in Alzheimer's disease (AD). The present study compares the levels of… 
Highly Cited
1986
Highly Cited
1986
Characterization of free radical-induced base damage in DNA at biologically relevant levels.
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