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5-hydroxyuracil

Known as: 2,4,5(3H)-Pyrimidinetrione, dihydro- 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Aging has been associated with damage accumulation in the genome and with increased cancer incidence. Reactive oxygen species… Expand
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Review
2007
Review
2007
Increasing evidence supports a role for oxidative DNA damage in aging and several neurodegenerative diseases including Alzheimer… Expand
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Highly Cited
2003
Highly Cited
2003
Repair of oxidatively damaged bases in the genome via the base excision repair pathway is initiated with excision of these… Expand
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Review
2002
Review
2002
  • S. Wallace
  • Free radical biology & medicine
  • 2002
  • Corpus ID: 11852794
The principal oxidized cytosine bases, uracil glycol, 5-hydroxycytosine, and 5-hydroxyuracil, are readily bypassed, miscode, and… Expand
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Highly Cited
2002
Highly Cited
2002
Two candidate human orthologs ofEscherichia coli MutM/Nei were recently identified in the human genome database, and one of these… Expand
Highly Cited
2002
Highly Cited
2002
The DNA glycosylase pathway, which requires the sequential action of two enzymes for the incision of DNA, presents a serious… Expand
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Highly Cited
1998
Highly Cited
1998
Abstract: Multiple lines of evidence indicate that oxidative stress is a contributor to neuronal death in Alzheimer's disease (AD… Expand
Highly Cited
1998
Highly Cited
1998
The most common base substitution arising from oxidative damage of DNA is a GC --> AT transition. In an effort to determine the… Expand
Highly Cited
1997
Highly Cited
1997
Abstract: Oxidative stress may contribute to neuronal loss in Alzheimer's disease (AD). The present study compares the levels of… Expand
Highly Cited
1997
Highly Cited
1997
Exposure of calf thymus DNA to hypochlorous acid/hypochlorite leads to extensive DNA base modification. Large concentration… Expand