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5-hydroxyrofecoxib

National Institutes of Health

Papers overview

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2019
2019
Abstract Alpinetin is a natural flavonoid showing a variety of pharmacological effects such as anti-inflammatory, anti-tumor and… 
2017
2017
Abstract 1. Bakuchiol, one of the main active compounds of Psoralea corylifolia, possesses a variety of pharmacological… 
2007
2007
We have previously reported that oral administration of [14C]rofecoxib to rats resulted in the long retention of radioactivity by… 
2003
2003
O-Glucuronidation of 5-hydroxyrofecoxib is the major biotransformation pathway of rofecoxib in human, rat, and dog. The… 
2003
2003
The metabolism of rofecoxib, a potent and selective inhibitor of cyclooxygenase-2, was examined in vitro using human liver… 
2003
2003
O-Glucuronidation of 5-hydroxyrofecoxib is the major biotransformation pathway of rofecoxib in human, rat, and dog. The… 
2002
2002
The disposition and metabolism of rofecoxib, a selective cyclooxygenase-2 inhibitor, were examined in healthy human subjects and… 
2001
2001
Rofecoxib is a potent and highly selective cyclooxygenase-2 inhibitor used for the treatment of osteoarthritis and pain… 
Highly Cited
2000
Highly Cited
2000
Absorption, distribution, metabolism, and excretion studies were conducted in rats and dogs with rofecoxib (VIOXX, MK-0966), a…