5-hydroxyrofecoxib
National Institutes of Health
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We have previously reported that oral administration of [14C]rofecoxib to rats resulted in the long retention of radioactivity by…
The metabolism of rofecoxib, a potent and selective inhibitor of cyclooxygenase-2, was examined in vitro using human liver…
O-Glucuronidation of 5-hydroxyrofecoxib is the major biotransformation pathway of rofecoxib in human, rat, and dog. The…