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5-hydroxycytosine

Known as: 2,5-Pyrimidinedione, 4-amino-1,6-dihydro- 
National Institutes of Health

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2 relations

Broader (1)

Cytosine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
DNA damage levels and biochemical repair capacities associated with XRCC1 deficiency.
Base excision repair (BER) is the major corrective pathway for most spontaneous, oxidative, and alkylation DNA base and sugar… 
Highly Cited
2001
Highly Cited
2001
Repair and mutagenic potential of oxaluric acid, a major product of singlet oxygen-mediated oxidation of 8-oxo-7,8-dihydroguanine.
Oxidative reactions within DNA commonly result in base modifications. Among the four DNA bases, guanine is the most susceptible… 
2000
2000
Spontaneous and osmium tetroxide-induced mutagenesis in an Escherichia coli strain deficient in both endonuclease III and endonuclease VIII.
Thymine glycol, uracil glycol, 5-hydroxycytosine and 5-hydroxyuracil are common base lesions produced by cellular metabolism as… 
Highly Cited
1999
Highly Cited
1999
The effect of experimental conditions on the levels of oxidatively modified bases in DNA as measured by gas chromatography-mass spectrometry: how many modified bases are involved? Prepurification or…
Highly Cited
1999
Highly Cited
1999
Repair of oxidative DNA base lesions induced by fluorescent light is defective in xeroderma pigmentosum group A cells.
Fluorescent light (FL) has been shown to generate free radicals within cells, however, the specific chemical nature of DNA damage… 
1998
1998
Substrate specificity of Schizosaccharomyces pombe Nth protein for products of oxidative DNA damage.
A gene from Schizosaccharomyces pombe, which encodes a protein with a strong sequence similarity to the Nth protein of… 
1996
1996
Excision of oxidative cytosine modifications from gamma-irradiated DNA by Escherichia coli endonuclease III and human whole-cell extracts.
The possible release from gamma-irradiated DNA of eight oxidatively modified cytosine bases by Escherichia coli endonuclease III… 
Highly Cited
1995
Highly Cited
1995
Oxidative damage to 5-methylcytosine in DNA.
Exposure of pyrimidines of DNA to ionizing radiation under aerobic conditions or oxidizing agents results in attack on the 5,6… 
1993
1993
A novel method for site specific introduction of single model oxidative DNA lesions into oligodeoxyribonucleotides.
Calf thymus terminal deoxynucleotidyl transferase was used to incorporate several products of oxidative base damage onto the 3… 
Highly Cited
1986
Highly Cited
1986
Formation of cytosine glycol and 5,6-dihydroxycytosine in deoxyribonucleic acid on treatment with osmium tetroxide.
OsO4 selectively forms thymine glycol lesions in DNA. In the past, OsO4-treated DNA has been used as a substrate in studies of… 
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