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The extensive literature and the work from our laboratory illustrate the large number of complex processes affected by estrogen… Expand The purpose of this study was to investigate the efficacy of a novel steroid, fluasterone (DHEF, a dehydroepiandrosterone (DHEA… Expand The combined effect of cosolvent (methanol (MeOH), ethanol (EtOH), or n-propanol (n-PrOH)) and complexant hydroxypropyl-beta… Expand Prostate cancer is the most common male malignancy in western countries. Although primary prevention of prostate cancer is not… Expand Experimental allergic encephalomyelitis (EAE), a Th1 polarized demyelinating disease of the central nervous system (CNS), shares… Expand Progress in mechanism-based cancer prevention research may be facilitated by the use of animal models displaying specific genetic… Expand Solubility enhancement has broad implications in parenteral formulation design. A simple mathematical model has been developed to… Expand Solubilization of nonpolar drugs constitutes one of the most important tasks in parenteral formulations design. This study… Expand Clinical chemoprevention trials of more than 30 agents and agent combinations are now in progress or being planned. The most… Expand Chemoprevention drug development has the goal of identifying safe and effective chemopreventive agents for clinical use. Several… Expand