Three-generation reproductive toxicity study of dietary bisphenol A in CD Sprague-Dawley rats.
- R. Tyl, C. Myers, J. Waechter
- BiologyToxicological Sciences
- 1 July 2002
BPA should not be considered a selective reproductive toxicant, based on the results of this study, and no evidence of nonmonotonic dose-response curves across generations for either sex is found.
Bisphenol A Exposure Causes Meiotic Aneuploidy in the Female Mouse
- P. Hunt, K. E. Koehler, T. Hassold
- BiologyCurrent Biology
- 1 April 2003
Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs
- B. Martin, D. R. Compton, J. WardSusan
- Biology, ChemistryPharmacology, Biochemistry and Behavior
- 1 November 1991
Comparative receptor binding analyses of cannabinoid agonists and antagonists.
- B. Thomas, A. Gilliam, D. F. Burch, M. Roche, H. Seltzman
- Biology, ChemistryJournal of Pharmacology and ExperimentalâŚ
- 1 April 1998
The results suggest that CP-55,940, WIN55212-2 and other agonists interact with cannabinoid binding sites within the brain which are distinguishable from the population of binding sites for SR141716A, its analogs and cannabidiol.
Potent rewarding and reinforcing effects of the synthetic cathinone 3,4âmethylenedioxypyrovalerone (MDPV)
- L. Watterson, P. Kufahl, M. Olive
- Psychology, BiologyAddiction Biology
- 1 March 2014
Findings indicate that MDPV has reinforcing properties and activates brain reward circuitry, suggesting a potential for abuse and addiction in humans.
Labeling Accuracy of Cannabidiol Extracts Sold Online
- M. Bonn-Miller, M. Loflin, B. Thomas, J. Marcu, Travis Hyke, R. Vandrey
- BiologyJAMA
- 7 November 2017
To maximize sampling and ensure representativeness of available products, this work examined the label accuracy of CBD products sold online, including identification of present but unlabeled cannabinoids.
Clinical characteristics and pharmacokinetics of purified soy isoflavones: single-dose administration to healthy men.
- M. Busby, A. Jeffcoat, S. Zeisel
- Medicine, BiologyAmerican Journal of Clinical Nutrition
- 2002
Dietary supplements of purified unconjugated isoflavones administered to humans in single doses exceeding normal dietary intake manyfold resulted in minimal clinical toxicity.
Î9-Tetrahydrocannbinol Accounts for the Antinociceptive, Hypothermic, and Cataleptic Effects of Marijuana in Mice
- S. Varvel, D. Bridgen, Q. Tao, B. Thomas, B. Martin, A. Lichtman
- Biology, PsychologyJournal of Pharmacology and ExperimentalâŚ
- 1 July 2005
Evidence is provided that the acute cannabinoid effects of marijuana smoke exposure on analgesia, hypothermia, and catalepsy in mice result from Î9-THC content acting at CB1 receptors and that the non-Î9- THC constituents of marijuana influence these effects only minimally, if at all.
AB-CHMINACA, AB-PINACA, and FUBIMINA: Affinity and Potency of Novel Synthetic Cannabinoids in Producing Î9-TetrahydrocannabinolâLike Effects in Mice
- J. Wiley, J. Marusich, B. Thomas
- Chemistry, BiologyJournal of Pharmacology and ExperimentalâŚ
- 1 September 2015
New synthetic cannabinoids examined exhibited higher efficacy than most known full agonists of the CB1 receptor and produced locomotor suppression, antinociception, hypothermia, and catalepsy in mice and in Î9-THC discrimination.
Effects of the abused solvent toluene on recombinant N-methyl-D-aspartate and non-N-methyl-D-aspartate receptors expressed in Xenopus oocytes.
- S. Cruz, T. Mirshahi, B. Thomas, R. Balster, J. Woodward
- Biology, ChemistryJournal of Pharmacology and ExperimentalâŚ
- 1 July 1998
The results suggest that some of the effects of toluene on neuronal activity and behavior may be mediated by inhibition of NMDA receptors.
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