5-Methoxytryptamine

Known as: Mexamine, 5-Methoxytryptamine [Chemical/Ingredient], 1H-Indole-3-ethanamine, 5-methoxy- 
Serotonin derivative proposed as potentiator for hypnotics and sedatives.
National Institutes of Health

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19 relations

Narrower (10)

4-nitro-5-methoxytryptamine5-methoxy-N,N-diisopropyltryptamine5-methoxy-N,N-diisopropyltryptamine N-oxide5-methoxy-N-isopropyltryptamine
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In Bloodagonistsanalogs & derivativesantagonists & inhibitors
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Broader (1)

tryptamine

Papers overview

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Review
2016
Review
2016
On the significance of an alternate pathway of melatonin synthesis via 5-methoxytryptamine: comparisons across species.
Melatonin is a phylogenetically ancient molecule. It is ubiquitously present in almost all organisms from primitive… (More)
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Highly Cited
2003
Highly Cited
2003
Regeneration of serotonin from 5-methoxytryptamine by polymorphic human CYP2D6.
Polymorphic cytochrome P450 2D6 (CYP2D6) is expressed in several types of central neurons but its function in human brain is… (More)
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2003
2003
Exogenously applied melatonin (N‐acetyl‐5‐methoxytryptamine) affects flowering of the short‐day plant Chenopodium rubrum
Melatonin (N-acetyl-5-methoxytryptamine) is an animal hormone synthesized predominantly at night. It often serves as a signal of… (More)
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Highly Cited
2000
Highly Cited
2000
The terminals of myenteric intrinsic primary afferent neurons of the guinea-pig ileum are excited by 5-hydroxytryptamine acting at 5-hydroxytryptamine-3 receptors
The aim of this study was to identify the receptor type(s) by which 5-hydroxytryptamine applied to the intestinal mucosa excites… (More)
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Review
1999
Review
1999
Melatonin and 5-methoxytryptamine in non-metazoans.
Melatonin seems to be an almost ubiquitous substance, which has been detected not only in metazoans, but also in all major non… (More)
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1996
1996
Metabolism of serotonin to N-acetylserotonin, melatonin, and 5-methoxytryptamine in hamster skin culture.
Biotransformation of [3H]serotonin by cultured hamster skin to 3H-metabolites corresponding to N-acetylserotonin (NAS), melatonin… (More)
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Review
1993
Review
1993
The significance of the metabolism of the neurohormone melatonin: Antioxidative protection and formation of bioactive substances
Recent findings suggest that the ability of melatonin to enter all body tissues and to be metabolized, enzymatically or… (More)
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Highly Cited
1988
Highly Cited
1988
A nonclassical 5-hydroxytryptamine receptor positively coupled with adenylate cyclase in the central nervous system.
A nonclassical 5-hydroxytryptamine (5-HT) receptor mediates the stimulation of adenylate cyclase activity in mouse embryo… (More)
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Highly Cited
1987
Highly Cited
1987
Characterization of a novel 3H-5-hydroxytryptamine binding site subtype in bovine brain membranes.
3H-5-Hydroxytryptamine (5-HT) binding sites were analyzed in bovine brain membranes. The addition of either the 5-HT1A-selective… (More)
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Highly Cited
1984
Highly Cited
1984
Neuronal 5-HT receptors in the periphery
5-Hydroxytryptamine (5-HT) induces responses in neurones from all branches of the mammalian peripheral nervous system. Responses… (More)
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