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5-Aminolevulinate synthase
Known as:
Aminolevulinic Acid Synthetase
, Synthetase, 5-Aminolevulinate
, delta Aminolevulinate Synthase
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An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta…
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National Institutes of Health
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Related topics
Related topics
12 relations
5-aminolevulinate synthase activity
ALAS1 gene
In Blood
Process of secretion
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Narrower (2)
ALAS2 protein, human
Protoporphyria, Erythropoietic, X-Linked Dominant
Broader (1)
Acyltransferase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1999
1999
Transcriptional regulation of 5-aminolevulinate synthase by phenobarbital and cAMP-dependent protein kinase.
C. Varone
,
L. Giono
,
A. Ochoa
,
M. Zakin
,
E. Cánepa
Archives of Biochemistry and Biophysics
1999
Corpus ID: 40318912
5-Aminolevulinate synthase (ALA-S) is a mitochondrial matrix enzyme that catalyzes the first and rate-limiting step of the heme…
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1998
1998
Role of arginine 439 in substrate binding of 5-aminolevulinate synthase.
D. Tan
,
T. Harrison
,
G. Hunter
,
G. C. Ferreira
Biochemistry
1998
Corpus ID: 2137025
5-Aminolevulinate synthase (EC 2.3.1.37) catalyzes the first reaction in the heme biosynthetic pathway in nonplant eukaryotes and…
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Highly Cited
1990
Highly Cited
1990
Transcriptional regulation of hydrogenase synthesis by nickel in Bradyrhizobium japonicum.
H. Kim
,
R. Maier
Journal of Biological Chemistry
1990
Corpus ID: 25525493
Nickel is a component of the H2-oxidizing hydrogenase of many bacteria. We report that nickel is required not only for the…
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1986
1986
Nucleotide sequence of the chicken 5-aminolevulinate synthase gene.
D. Maguire
,
A. Day
,
+4 authors
W. H. Elliott
Nucleic Acids Research
1986
Corpus ID: 45088502
5-Aminolevulinate synthase, the first and rate-controlling enzyme of heme biosynthesis, is regulated in the liver by the end…
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Highly Cited
1978
Highly Cited
1978
Heme is necessary for the accumulation and assembly of cytochrome c oxidase subunits in Saccharomyces cerevisiae.
J. Saltzgaber-Müller
,
G. Schatz
Journal of Biological Chemistry
1978
Corpus ID: 21177426
Highly Cited
1977
Highly Cited
1977
Increased erythrocyte uroporphyrinogen-l-synthetase, delta-aminolevulinic acid dehydratase and protoporphyrin in hemolytic anemias.
K. Anderson
,
S. Sassa
,
C. Peterson
,
A. Kappas
American Journal of Medicine
1977
Corpus ID: 45723052
Highly Cited
1973
Highly Cited
1973
STUDIES IN PORPHYRIA
H. Bradlow
,
Peter N. Gillette
,
T. Gallagher
,
A. Kappas
Journal of Experimental Medicine
1973
Corpus ID: 10729940
Patients with the genetic liver disease, acute intermittent porphyria (AIP), have a defect in the reductive transformation of…
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Highly Cited
1970
Highly Cited
1970
Controls on chlorophyll synthesis in barley.
K. Nadler
,
S. Granick
Plant Physiology
1970
Corpus ID: 19391915
In 7- to 10-day-old leaves of etiolated barley (Hordeum vulgare), all of the enzymes that convert delta-aminolevulinic acid to…
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Highly Cited
1970
Highly Cited
1970
Erythropoietic activity of steroid metabolites in mice.
D. Gorshein
,
F. Gardner
Proceedings of the National Academy of Sciences…
1970
Corpus ID: 28761460
The per cent Fe(59) incorporation into circulating erythrocytes as an indicator for new hemoglobin production was used in the…
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Highly Cited
1969
Highly Cited
1969
Mechanism of allylisopropylacetamide-induced increase of delta-aminolevulinate synthetase in liver mitochondria. IV. Accumulation of the enzyme in the soluble fraction of rat liver.
N. Hayashi
,
B. Yoda
,
G. Kikuchi
Archives of Biochemistry and Biophysics
1969
Corpus ID: 44652847
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