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5-Aminolevulinate synthase

Known as: Aminolevulinic Acid Synthetase, Synthetase, 5-Aminolevulinate, delta Aminolevulinate Synthase 
An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Exercise results in rapid increases in expression of the transcription coactivator peroxisome proliferator-activated receptor… Expand
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Highly Cited
1995
Highly Cited
1995
Heme is a prosthetic group for numerous enzymes, cytochromes and globins, and it binds tightly, sometimes covalently, to these… Expand
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Highly Cited
1993
Highly Cited
1993
A conserved motif, termed the heme regulatory motif (HRM), was identified in the presequences of the erythroid delta… Expand
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Highly Cited
1991
Highly Cited
1991
5‐Aminolevulinate synthase (ALAS) catalyzes the first step of the heme biosynthetic pathway. cDNA clones for the human erythroid… Expand
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Highly Cited
1982
Highly Cited
1982
A symbiotically important gene system in rhizobial species is the heme biosynthetic pathway. A mutant having reduced levels of… Expand
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Highly Cited
1975
Highly Cited
1975
The final step in heme biosynthesis is chelation of porphyrin with Fe++ catalyzed by the mitochondrial enzyme heme synthetase. We… Expand
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Highly Cited
1966
Highly Cited
1966
  • S. Granick
  • The Journal of biological chemistry
  • 1966
  • Corpus ID: 20808677
Abstract 1. A method is described for the primary growth of chick embryo liver cells on cover slips in culture, and the factors… Expand
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Highly Cited
1966
Highly Cited
1966
Abstract Administration of allylisopropylacetamide to rats causes a marked increase in the hepatic ribonucleic acid-dependent… Expand
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Highly Cited
1966
Highly Cited
1966
Abstract δ-Aminolevulinic acid synthesis has been demonstrated in both porphyric and normal liver homogenates. A study of the… Expand
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Highly Cited
1963