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5,6-dihydrothymine

Known as: 5-methyldihydrouracil 
National Institutes of Health

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2 relations

Broader (1)

Thymine
analogs & derivatives

Papers overview

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2010
2010
Fluorescent probes for the analysis of DNA strand scission in base excision repair
We have developed fluorescent probes for the detection of strand scission in the excision repair of oxidatively damaged bases… 
2007
2007
Use of damaged DNA and dNTP substrates by the error-prone DNA polymerase X from African swine fever virus.
The structural specificity that translesion DNA polymerases often show for a particular class of lesions suggests that the… 
2006
2006
Contributions of an endonuclease IV homologue to DNA repair in the African swine fever virus.
We recently demonstrated that African swine fever virus DNA polymerase X (Pol X) is extremely error-prone during single… 
2004
2004
Quantification of 5,6-dihydrouracil by HPLC-electrospray tandem mass spectrometry.
In humans, the pathway for the catabolism of uracil and thymine consists of three consecutive steps. Dihydropyrimidine… 
2002
2002
Acyclic nucleoside analogues as novel inhibitors of human mitochondrial thymidine kinase.
A series of acyclic nucleoside analogues of 5'-O-tritylthymidine have been synthesized and evaluated as potential human… 
1998
1998
No circadian variation of dihydropyrimidine dehydrogenase, uridine phosphorylase, beta-alanine, and 5-fluorouracil during continuous infusion of 5-fluorouracil.
Dihydropyrimidine dehydrogenase (DPD, EC 1.3.1.2) is the initial and rate-limiting enzyme in the catabolism of the pyrimidine… 
1998
1998
Gas chromatography-mass spectrometry with high-performance liquid chromatography prepurification for monitoring the endonuclease III-mediated excision of 5-hydroxy-5,6-dihydrothymine and 5,6…
The endonuclease III from Escherichia coli is a repair enzyme which exhibits both a glycosylase and an endonuclease function. The… 
1993
1993
Ab initio theoretical study of the structures of thymine glycol and dihydrothymine.
The structures of all diastereoisomers of 5,6-dihydroxy-5,6-dihydrothymine (thymine glycol) an 5,6-dihydrothymine, two important… 
1989
1989
Purification and properties of 5,6-dihydropyrimidine amidohydrolase from calf liver.
5,6-Dihydropyrimidine amidohydrolase was isolated from an acetone powder of calf liver and purified to homogeneity. Purification… 
1987
1987
Radiation damage to dinucleoside monophosphates: mediated versus direct damage.
The mediation of radiation-induced damage to dinucleoside monophosphate by oxygen and by glutathione was studied. The sequence… 
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