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5'-3' exonuclease activity

Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 5' end. [GOC:ai]
National Institutes of Health

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3'-5' exonuclease activity

Papers overview

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2014
2014
Effects of cations on small fragment of DNA polymerase I using a novel FRET assay.
DNA polymerase I (PolI) digested by protease produces a small fragment (SF) containing 5'-3' exonuclease activity. The 5'-3… Expand
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Highly Cited
2010
Highly Cited
2010
A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair.
The Fanconi anemia (FA) pathway is responsible for interstrand crosslink repair. At the heart of this pathway is the FANCI-FAND2… Expand
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2010
2010
Role of RecJ-like Protein with 5′-3′ Exonuclease Activity in Oligo(deoxy)nucleotide Degradation*
RecJ-like proteins belonging to the DHH family have been proposed to function as oligoribonucleases and 3′-phosphoadenosine 5… Expand
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2007
2007
Reassessment of the in vivo functions of DNA polymerase I and RNase H in bacterial cell growth.
A major factor in removing RNA primers during the processing of Okazaki fragments is DNA polymerase I (Pol I). Pol I is thought… Expand
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Highly Cited
2003
Highly Cited
2003
CRN-1, a Caenorhabditis elegans FEN-1 homologue, cooperates with CPS-6/EndoG to promote apoptotic DNA degradation.
Oligonucleosomal fragmentation of chromosomes in dying cells is a hallmark of apoptosis. Little is known about how it is executed… Expand
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Highly Cited
2002
Highly Cited
2002
NurA, a novel 5'-3' nuclease gene linked to rad50 and mre11 homologs of thermophilic Archaea.
We isolated and characterized a new nuclease (NurA) exhibiting both single-stranded endonuclease activity and 5'-3' exonuclease… Expand
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1998
1998
A 5'-3' exonuclease activity involved in forming the 3' products of histone pre-mRNA processing in vitro.
Histone RNA 3' processing in vitro produces one or more 5' cleavage products corresponding to the mature histone mRNA 3' end, and… Expand
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1994
1994
Computer aided identification of a potential 5'-3' exonuclease gene encoded by Escherichia coli.
  • Jon R. Sayers
  • Journal of theoretical biology
  • 1994
    • Corpus ID: 38296546
The predicted amino acid sequence of a previously overlooked open reading frame (ORF) from E. coli has been subjected to sequence… Expand
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Highly Cited
1994
Highly Cited
1994
The characterization of a mammalian DNA structure-specific endonuclease.
The repair of some types of DNA double-strand breaks is thought to proceed through DNA flap structure intermediates. A DNA flap… Expand
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1990
1990
Properties of overexpressed phage T5 D15 exonuclease. Similarities with Escherichia coli DNA polymerase I 5'-3' exonuclease.
The D15 gene of the bacteriophage T5, thought to encode an exonuclease, was cloned into an M13 phage on a 1344-base pair fragment… Expand
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