4-quinolone-3-carboxylic acid
National Institutes of Health
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A series of 4-quinolone-3-carboxylic acid-containing spirooxindole-pyrrolidine derivatives was synthesized via multicomponent 1,3…
4-Quinolone-3-carboxamide derivatives have long been recognized as potent and selective cannabinoid type-2 receptor (CB2R…
Abstract A new class of 4-hydroxyquinoline-3-carbohydrazide derivatives was prepared and evaluated for its anti-HIV activity. The…
Three heterocyclic systems were selected as potential bioisosteres of the amide linker for a series of 1,6‐disubstituted‐4…
Experimental evidence suggests that selective CB2 receptor modulators may provide access to antihyperalgesic agents devoid of…
A set of quinolone-3-carboxamides 2 bearing diverse substituents at position 1, 3, and 6 of the bicyclic nucleus was prepared…
Quinolones are among the most common frameworks present in the bioactive molecules and hence represent an attractive starting…
A set of 4-quinolone-3-carboxylic acids bearing different substituents on the condensed benzene ring was designed and synthesized…
Quinolone-3-carboxamides 11 bearing at position 5, 6, 7, or 8 diverse substituents such as halides, alkyl, aryl, alkoxy, and…
Novel 1-trifluoromethyl-4-quinolone derivatives (8a,b) were synthesized, and the antibacterial activity of each was evaluated. An…