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4-oxoretinol

Known as: 4-ketoretinol 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Vitamin A
analogs & derivatives

Papers overview

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2009
2009
Metabolism and regulation of gene expression by 4‐oxoretinol versus all‐trans retinoic acid in normal human mammary epithelial cells
We previously demonstrated that 4‐oxoretinol (4‐oxo‐ROL) activated retinoic acid receptors (RARs) in F9 stem cells. We showed… 
2008
2008
Metabolism and biological activities of topical 4-oxoretinoids in mouse skin.
Retinoic acid mediates most of the biological actions of vitamin A. It is oxidized by CYP26A1 to 4-oxoretinoic acid, considered… 
2008
2008
LIF removal increases CRABPI and CRABPII transcripts in embryonic stem cells cultured in retinol or 4-oxoretinol
2006
2006
Human Breast Cancer Cells and Normal Mammary Epithelial Cells : Retinol Metabolism and Growth Inhibition by the Retinol Metabolite 4-Oxoretinol 1
To understand the signaling and growth-inhibitory effects of retinoids, we have examined the metabolism of I'll liTtinol in a… 
2005
2005
Elevated serum concentrations of beta-glucuronide metabolites and 4-oxoretinol in lactating sows after treatment with vitamin A: a model for evaluating supplementation in lactating women.
BACKGROUND The effects of large doses of preformed vitamin A, such as those provided in supplementation programs for the… 
Highly Cited
1999
Highly Cited
1999
Removal of LIF (leukemia inhibitory factor) results in increased vitamin A (retinol) metabolism to 4-oxoretinol in embryonic stem cells.
Retinoids, vitamin A (retinol) and its metabolic derivatives, are required for normal vertebrate development. In murine embryonic… 
1999
1999
Analysis of cyclic and acyclic analogs of retinol, retinoic acid, and retinal by laser desorption ionization-, matrix-assisted laser desorption ionization-mass spectrometry, and UV/Vis spectroscopy.
Laser desorption ionization (LDI)- and matrix-assisted laser desorption ionization (MALDI)-mass spectrometry (LDI-MS, MALDI-MS… 
Highly Cited
1997
Highly Cited
1997
Human breast cancer cells and normal mammary epithelial cells: retinol metabolism and growth inhibition by the retinol metabolite 4-oxoretinol.
To understand the signaling and growth-inhibitory effects of retinoids, we have examined the metabolism of [3H]retinol in a… 
Highly Cited
1996
Highly Cited
1996
4-Oxoretinol, a new natural ligand and transactivator of the retinoic acid receptors.
All-trans-retinoic acid (at-RA) induces cell differentiation in a wide variety of cell types, including F9 embryonic… 
Highly Cited
1996
Highly Cited
1996
Novel retinoic acid receptor ligands in Xenopus embryos.
Retinoids are a large family of natural and synthetic compounds related to vitamin A that have pleiotropic effects on body… 
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