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4-oxoretinol
Known as:
4-ketoretinol
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Vitamin A
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Metabolism and regulation of gene expression by 4‐oxoretinol versus all‐trans retinoic acid in normal human mammary epithelial cells
Limin Liu
,
F. Derguini
,
L. Gudas
Journal of cellular physiology
2009
Corpus ID: 3414530
We previously demonstrated that 4‐oxoretinol (4‐oxo‐ROL) activated retinoic acid receptors (RARs) in F9 stem cells. We showed…
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2008
2008
Metabolism and biological activities of topical 4-oxoretinoids in mouse skin.
O. Sorg
,
C. Tran
,
+6 authors
J. Saurat
The Journal of investigative dermatology
2008
Corpus ID: 10716759
Retinoic acid mediates most of the biological actions of vitamin A. It is oxidized by CYP26A1 to 4-oxoretinoic acid, considered…
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2008
2008
LIF removal increases CRABPI and CRABPII transcripts in embryonic stem cells cultured in retinol or 4-oxoretinol
M. Lane
,
Juliana Xu
,
E. Wilen
,
R. Sylvester
,
F. Derguini
,
L. Gudas
Molecular and Cellular Endocrinology
2008
Corpus ID: 20817042
2006
2006
Human Breast Cancer Cells and Normal Mammary Epithelial Cells : Retinol Metabolism and Growth Inhibition by the Retinol Metabolite 4-Oxoretinol 1
Anne C. Chen
,
Xiaojia
,
Guo
,
F. Derguini
,
Lorraine
,
J. Gudas
2006
Corpus ID: 15347915
To understand the signaling and growth-inhibitory effects of retinoids, we have examined the metabolism of I'll liTtinol in a…
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2005
2005
Elevated serum concentrations of beta-glucuronide metabolites and 4-oxoretinol in lactating sows after treatment with vitamin A: a model for evaluating supplementation in lactating women.
K. Penniston
,
S. Tanumihardjo
The American journal of clinical nutrition
2005
Corpus ID: 4466359
BACKGROUND The effects of large doses of preformed vitamin A, such as those provided in supplementation programs for the…
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Highly Cited
1999
Highly Cited
1999
Removal of LIF (leukemia inhibitory factor) results in increased vitamin A (retinol) metabolism to 4-oxoretinol in embryonic stem cells.
M. Lane
,
A. C. Chen
,
S. Roman
,
F. Derguini
,
L. Gudas
Proceedings of the National Academy of Sciences…
1999
Corpus ID: 29324948
Retinoids, vitamin A (retinol) and its metabolic derivatives, are required for normal vertebrate development. In murine embryonic…
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1999
1999
Analysis of cyclic and acyclic analogs of retinol, retinoic acid, and retinal by laser desorption ionization-, matrix-assisted laser desorption ionization-mass spectrometry, and UV/Vis spectroscopy.
T. Wingerath
,
D. Kirsch
,
B. Spengler
,
W. Stahl
Analytical biochemistry
1999
Corpus ID: 25825420
Laser desorption ionization (LDI)- and matrix-assisted laser desorption ionization (MALDI)-mass spectrometry (LDI-MS, MALDI-MS…
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Highly Cited
1997
Highly Cited
1997
Human breast cancer cells and normal mammary epithelial cells: retinol metabolism and growth inhibition by the retinol metabolite 4-oxoretinol.
A. C. Chen
,
X. Guo
,
F. Derguini
,
L. Gudas
Cancer research
1997
Corpus ID: 39689270
To understand the signaling and growth-inhibitory effects of retinoids, we have examined the metabolism of [3H]retinol in a…
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Highly Cited
1996
Highly Cited
1996
4-Oxoretinol, a new natural ligand and transactivator of the retinoic acid receptors.
C. Achkar
,
F. Derguini
,
+8 authors
L. Gudas
Proceedings of the National Academy of Sciences…
1996
Corpus ID: 1760352
All-trans-retinoic acid (at-RA) induces cell differentiation in a wide variety of cell types, including F9 embryonic…
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Highly Cited
1996
Highly Cited
1996
Novel retinoic acid receptor ligands in Xenopus embryos.
B. Blumberg
,
J. Bolado
,
+6 authors
R. Evans
Proceedings of the National Academy of Sciences…
1996
Corpus ID: 22006922
Retinoids are a large family of natural and synthetic compounds related to vitamin A that have pleiotropic effects on body…
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