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4-oxo-2-nonenal

Known as: 4-oxonon-2-enal 
 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Lipid electrophiles modify cellular targets, altering their function. Here, we describe histones as major targets for… Expand
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Highly Cited
2011
Highly Cited
2011
Oxidative stress has been implicated in the etiology of neurodegenerative disorders with α-synuclein pathology. Lipid… Expand
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Highly Cited
2006
Highly Cited
2006
Previous studies found the lipid peroxidation product 4-hydroxynon-2-enal (4HNE) to be both a substrate and an inhibitor of… Expand
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Highly Cited
2005
Highly Cited
2005
Electrophilic aldehydes, generated from oxidation of polyunsaturated fatty acyl chains under conditions of oxidative stress, bind… Expand
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2003
2003
The modification of proteins by 4-hydroxy-2-nonenal (HNE) and 4-oxo-2-nonenal (ONE) was investigated using mass spectroscopic… Expand
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2003
2003
trans-4-Oxo-2-nonenal (ONE) has recently been demonstrated to be a direct product of lipid peroxidation. In earlier studies to… Expand
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Highly Cited
2002
Highly Cited
2002
Lipid peroxidation yields the aldehydes 4-hydroxynonenal (4HNE) and 4-oxononenal (4ONE). Protein adduction by 4HNE is thought to… Expand
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Highly Cited
2001
Highly Cited
2001
Epidemiological data suggest that dietary antioxidants play a protective role against cancer. This has led to the proposal that… Expand
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Highly Cited
2000
Highly Cited
2000
Fe(II)-mediated decomposition of 13-[S-(Z,E)]-9, 11-hydroperoxyoctadecadienoic (hydroperoxylinoleic) acid resulted in the… Expand
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1999
1999
Two major products (adducts A and B) from the reaction of 2-deoxyguanosine (dGuo) with 13-hydroperoxylinoleic acid were detected… Expand
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