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4-oxo-2-nonenal

Known as: 4-oxonon-2-enal 
 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Lipid electrophiles modify cellular targets, altering their function. Here, we describe histones as major targets for… Expand
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Highly Cited
2011
Highly Cited
2011
Oxidative stress has been implicated in the etiology of neurodegenerative disorders with α-synuclein pathology. Lipid… Expand
Highly Cited
2005
Highly Cited
2005
Electrophilic aldehydes, generated from oxidation of polyunsaturated fatty acyl chains under conditions of oxidative stress, bind… Expand
Highly Cited
2003
Highly Cited
2003
The modification of proteins by 4-hydroxy-2-nonenal (HNE) and 4-oxo-2-nonenal (ONE) was investigated using mass spectroscopic… Expand
Highly Cited
2003
Highly Cited
2003
trans-4-Oxo-2-nonenal (ONE) has recently been demonstrated to be a direct product of lipid peroxidation. In earlier studies to… Expand
Highly Cited
2002
Highly Cited
2002
Lipid peroxidation yields the aldehydes 4-hydroxynonenal (4HNE) and 4-oxononenal (4ONE). Protein adduction by 4HNE is thought to… Expand
Highly Cited
2001
Highly Cited
2001
Epidemiological data suggest that dietary antioxidants play a protective role against cancer. This has led to the proposal that… Expand
Highly Cited
2000
Highly Cited
2000
  • S. Lee, I. Blair
  • Chemical research in toxicology
  • 2000
  • Corpus ID: 10251759
Fe(II)-mediated decomposition of 13-[S-(Z,E)]-9, 11-hydroperoxyoctadecadienoic (hydroperoxylinoleic) acid resulted in the… Expand
Highly Cited
2000
Highly Cited
2000
Analysis of the reaction between 2'-deoxyadenosine and 4-oxo-2-nonenal by liquid chromatography/mass spectrometry revealed the… Expand
Highly Cited
1999
Highly Cited
1999
Two major products (adducts A and B) from the reaction of 2-deoxyguanosine (dGuo) with 13-hydroperoxylinoleic acid were detected… Expand