Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

4-oxalocrotonate tautomerase

Known as: 4-oxalocrotonate isomerase 
 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Isomerase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Biocatalytic Michael-type additions of acetaldehyde to nitroolefins with the proline-based enzyme 4-oxalocrotonate tautomerase yielding enantioenriched γ-nitroaldehydes.
Call me Michaelase: The enzyme 4-oxalocrotonate tautomerase (4-OT) promiscuously catalyzes the Michael-type addition of… Expand
Is this relevant?
Review
2008
Review
2008
The chemical versatility of the β–α–β fold: Catalytic promiscuity and divergent evolution in the tautomerase superfamily
Abstract.Tautomerase superfamily members have an amino-terminal proline and a β–α–β fold, and include 4-oxalocrotonate… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2007
2007
Quantum chemical modeling of enzymatic reactions: the case of 4-oxalocrotonate tautomerase.
The reaction mechanism of 4-oxalocrotonate tautomerase (4-OT) is studied using the density functional theory method B3LYP. This… Expand
Is this relevant?
2006
2006
Evolution of enzymatic activity in the tautomerase superfamily: mechanistic and structural consequences of the L8R mutation in 4-oxalocrotonate tautomerase.
4-Oxalocrotonate tautomerase (4-OT) and trans-3-chloroacrylic acid dehalogenase (CaaD) are members of the tautomerase superfamily… Expand
Is this relevant?
Review
2002
Review
2002
The 4-oxalocrotonate tautomerase family of enzymes: how nature makes new enzymes using a beta-alpha-beta structural motif.
4-Oxalocrotonate tautomerase (4-OT) catalyzes the isomerization of beta,gamma-unsaturated enones to their alpha,beta-isomers. The… Expand
Is this relevant?
2001
2001
trans-3-Chloroacrylic acid dehalogenase from Pseudomonas pavonaceae 170 shares structural and mechanistic similarities with 4-oxalocrotonate tautomerase.
The genes (caaD1 and caaD2) encoding the trans-3-chloroacrylic acid dehalogenase (CaaD) of the 1,3-dichloropropene-utilizing… Expand
  • table 1
  • table 2
  • figure 1
  • table 3
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Crystal structure of human D-dopachrome tautomerase, a homologue of macrophage migration inhibitory factor, at 1.54 A resolution.
D-Dopachrome tautomerase shares a low homologous amino acid sequence (33% homology) with the macrophage migration inhibitory… Expand
Is this relevant?
1996
1996
4-Oxalocrotonate tautomerase: pH dependence of catalysis and pKa values of active site residues.
The pH-rate profiles for the kinetic parameters of 4-oxalocrotonate tautomerase (4-OT) have been measured using 2-hydroxy-2,4… Expand
Is this relevant?
1996
1996
15N NMR relaxation studies of free and inhibitor-bound 4-oxalocrotonate tautomerase: backbone dynamics and entropy changes of an enzyme upon inhibitor binding.
The solution secondary structure of 4-oxalocrotonate tautomerase (4-OT), a 41 kDa homohexamer with 62 residues per subunit… Expand
Is this relevant?
1992
1992
4-Oxalocrotonate tautomerase, an enzyme composed of 62 amino acid residues per monomer.
The xylH gene encoding 4-oxalocrotonate tautomerase (4-OT) has been located on a subclone of the Pseudomonas putida mt-2 TOL… Expand
  • table I
  • figure 1
  • figure 2
  • table I
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE