Variations in Depleted Uranium Sorption and Solubility with Depth in Arid Soils
This study examined the ability of alkaline desert soils to sorb depleted uranium (DU) as a function of soil horizon and assessed the solubility of corrosion and migration products from two DU…
The sorption of selenite on various cement formulations
Oral administration of naturally occurring coumarins leads to altered phase I and II enzyme activities and reduced DNA adduct formation by polycyclic aromatic hydrocarbons in various tissues of…
- H. Kleiner, S. Vulimiri, L. Miller, W. Johnson, C. P. Whitman, J. DiGiovanni
- Chemistry, BiologyCarcinogenesis
The results suggest that imperatorin and isopimpinellin may have potential chemopreventive effects when administered in the diet.
Crystal structure of 4-oxalocrotonate tautomerase inactivated by 2-oxo-3-pentynoate at 2.4 A resolution: analysis and implications for the mechanism of inactivation and catalysis.
- A. Taylor, R. Czerwinski, W. Johnson, C. P. Whitman, M. Hackert
- Chemistry, BiologyBiochemistry
- 20 October 1998
The crystal structure of 4-oxalocrotonate tautomerase (4-OT) inactivated by the active site-directed irreversible inhibitor 2-oxo-3-pentynoate has been determined and a mechanism for the enzyme-catalyzed reaction is proposed.
Developing resilient ponderosa pine forests with mechanical thinning and prescribed fire in central Oregon's pumice region
Thinning served as an effective surrogate to fire for managing central Oregon forest vegetation and helped restore natural ecological function, according to a comparison of treatment combinations for two decades.
Design of composite SC walls to prevent perforation from missile impact
Crystal structure of macrophage migration inhibitory factor complexed with (E)-2-fluoro-p-hydroxycinnamate at 1.8 A resolution: implications for enzymatic catalysis and inhibition.
- A. Taylor, W. Johnson, R. Czerwinski, H. Li, M. Hackert, C. P. Whitman
- Chemistry, BiologyBiochemistry
- 8 June 1999
A mechanism is proposed for the MIF-catalyzed tautomerization reaction and it is demonstrated that MIF processes the enol isomers more efficiently than the keto isomers primarily because of a decrease in Km.
The structure of the proline utilization a proline dehydrogenase domain inactivated by N-propargylglycine provides insight into conformational changes induced by substrate binding and flavin…
- D. Srivastava, Weidong Zhu, W. Johnson, C. P. Whitman, D. Becker, J. Tanner
- Biology, ChemistryBiochemistry
- 26 January 2010
It is shown that N-propargylglycine irreversibly inactivates PutA by covalently linking the flavin N(5) atom to the epsilon-amino of Lys329, and inactivation locks PutA into a conformation that may mimic the proline-reduced, membrane-associated form.
Kinetic and structural effects of mutations of the catalytic amino-terminal proline in 4-oxalocrotonate tautomerase.
It is concluded that the 2 order of magnitude decreases in kcat in the P1G and P1A mutants result from both a decrease in basicity and an increase in flexibility of the general base.
Corrosion of Depleted Uranium in an Arid Environment: Soil-Geomorphology, SEM/EDS, XRD, and Electron Microprobe Analyses
Corrosion of anthropogenic uranium in natural environments is not well understood, but is important for determining potential health risks and mobility in the environment. A site in the southwestern…