W. Johnson

Publications111
h-index23
Citations1,497
Highly Influential Citations24
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Variations in Depleted Uranium Sorption and Solubility with Depth in Arid Soils
This study examined the ability of alkaline desert soils to sorb depleted uranium (DU) as a function of soil horizon and assessed the solubility of corrosion and migration products from two DU… Expand
Crystal structure of 4-oxalocrotonate tautomerase inactivated by 2-oxo-3-pentynoate at 2.4 A resolution: analysis and implications for the mechanism of inactivation and catalysis.
TLDR
The crystal structure of 4-oxalocrotonate tautomerase (4-OT) inactivated by the active site-directed irreversible inhibitor 2-oxo-3-pentynoate has been determined and a mechanism for the enzyme-catalyzed reaction is proposed. Expand
Kinetic and structural effects of mutations of the catalytic amino-terminal proline in 4-oxalocrotonate tautomerase.
TLDR
It is concluded that the 2 order of magnitude decreases in kcat in the P1G and P1A mutants result from both a decrease in basicity and an increase in flexibility of the general base. Expand
The sorption of selenite on various cement formulations
Abstract Twenty-seven cementitious formulations containing three levels of water/solids ratio (0.45, 0.50, and 0.55), three concentrations of silica fume (0, 10, and 20%), and three concentrations of… Expand
Oral administration of naturally occurring coumarins leads to altered phase I and II enzyme activities and reduced DNA adduct formation by polycyclic aromatic hydrocarbons in various tissues of…
TLDR
The results suggest that imperatorin and isopimpinellin may have potential chemopreventive effects when administered in the diet. Expand
Crystal structure of macrophage migration inhibitory factor complexed with (E)-2-fluoro-p-hydroxycinnamate at 1.8 A resolution: implications for enzymatic catalysis and inhibition.
TLDR
A mechanism is proposed for the MIF-catalyzed tautomerization reaction and it is demonstrated that MIF processes the enol isomers more efficiently than the keto isomers primarily because of a decrease in Km. Expand
The structure of the proline utilization a proline dehydrogenase domain inactivated by N-propargylglycine provides insight into conformational changes induced by substrate binding and flavin…
TLDR
It is shown that N-propargylglycine irreversibly inactivates PutA by covalently linking the flavin N(5) atom to the epsilon-amino of Lys329, and inactivation locks PutA into a conformation that may mimic the proline-reduced, membrane-associated form. Expand
Effects of flue-curing and ageing on the volatile, neutral and acidic constituents of Virginia tobacco☆
Abstract Several volatile compounds are generated and the concentrations of many others increase on flue-curing and ageing of Virginia tobacco. Oxidative degradation of isoprenoids, Maillard… Expand
Stereochemical and isotopic labeling studies of 2-oxo-hept-4-ene-1,7- dioate hydratase: Evidence for an enzyme-catalyzed ketonization step in the hydration reaction
2-Oxo-hept-4-ene-1,7-dioate hydratase from Escherichia coli C converts 2-oxo-hept-4-ene-1,7-dioate to 2-oxo-4-hydroxy-hepta-1,7-dioate by the addition of water using magnesium as a cofactor. The… Expand
Corrosion of Depleted Uranium in an Arid Environment: Soil-Geomorphology, SEM/EDS, XRD, and Electron Microprobe Analyses
Corrosion of anthropogenic uranium in natural environments is not well understood, but is important for determining potential health risks and mobility in the environment. A site in the southwestern… Expand
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