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4-hydroxypropranolol

Known as: 1-(4-hydroxynaphth-1-yloxy)-3-isopropylamino-2- propanol, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-1-naphthalenol 
 
National Institutes of Health

Papers overview

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2014
2014
The purpose of this paper was to study at the molecular level the enantioseparation mechanism of 4-hydroxypropranolol (4-OH-Prop… Expand
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2009
2009
A CE method is described for the enantioselective analysis of propranolol (Prop) and 4-hydroxypropranolol (4-OH-Prop) in liquid… Expand
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2001
2001
Repetitive administration of propranolol (PL) in rats decreases the activities of cytochrome P450 (CYP) 2D enzyme(s) in hepatic… Expand
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1995
1995
Propranolol pharmacokinetics among different genotypes of CYP2D6 was compared in this study. The Chinese (Han) population… Expand
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Highly Cited
1989
Highly Cited
1989
The relative contributions of the debrisoquin and mephenytoin isozymes of hepatic cytochrome P-450 to the stereoselective… Expand
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1984
1984
The ability to hydroxylate debrisoquine is known to be polymorphically distributed, with about 8% to 9% of the North American… Expand
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1982
1982
1 We have given fifteen healthy volunteers single doses of racemic (+/-)-propranolol orally (40 mg) and intravenously (5-10 mg… Expand
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1980
1980
The disposition of the pharmacologically active 4-hydroxypropranolol (HO-P), its glucuronic acid conjugate (HO-P-G), and… Expand
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1978
1978
A simple and rapid high-pressure liquid chromatographic procedure is reported for the simultaneous quantitative determination of… Expand
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1971
1971
1. 4-Hydroxypropranolol, a metabolite produced after oral administration of propranolol, has been shown to be a beta-adrenoceptor… Expand
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