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4-hydroxyclomiphene

National Institutes of Health

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2 relations

Broader (1)

Clomiphene
analogs & derivatives

Papers overview

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Highly Cited
1991
Highly Cited
1991
Retinoic acid acts synergistically with 1,25-dihydroxyvitamin D3 or antioestrogen to inhibit T-47D human breast cancer cell proliferation
1989
1989
Phenolic metabolites of clomiphene: [(E,Z)-2-[4-(1,2-diphenyl-2-chlorovinyl)phenoxy]ethyl]diethylamine. Preparation, electrophilicity, and effects in MCF 7 breast cancer cells.
The triarylethylene antiestrogen clomiphene was previously shown to undergo biotransformation to an active metabolite, 4… 
Highly Cited
1987
Highly Cited
1987
Epidermal growth factor partially reverses the inhibitory effects of antiestrogens on T 47D human breast cancer cell growth.
1986
1986
Substituted-vinyl hydroxytriarylethylenes, 1-[4-[2-(diethylamino) ethoxy]phenyl]-1-(4-hydroxyphenyl)-2-phenylethylenes: synthesis and effects on MCF 7 breast cancer cell proliferation.
A series of triarylethylene compounds related to 4-hydroxyclomiphene (2) in which the vinyl Cl substituent was replaced by ethyl… 
1983
1983
Metabolism of clomiphene in the rat. Estrogen receptor affinity and antiestrogenic activity of clomiphene metabolites.
1981
1981
Rabbit liver microsomal metabolism of enclomiphene.
Metabolism of the triarylethylene antiestrogen enclomiphene (EC) has been studied in rabbit liver. Incubation of EC with… 
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