4-chloro-N-methylaniline demethylase

Known as: PCMADase, p-chloro-N-methylaniline demethylase, para-chloro-N-methylaniline demethylase 
 
National Institutes of Health

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Oxidoreductases, N-Demethylating

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2010
2010
Design and synthesis of 2-chloroquinoline derivatives as non-azoles antimycotic agents
A series of secondary amines (4–19) containing 2-chloroquinoline as lipophilic domain have been synthesized based on the… (More)
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1998
1998
Cytochrome P450 purification and immunological detection in an insecticide resistant strain of German cockroach (Blattella germanica, L.).
A German cockroach strain, Munsyana (MA) had 80-fold resistance to the pyrethroid insecticide cypermethrin, 4.5-fold greater… (More)
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1997
1997
An evaluation of the DNA damaging effect of selected aniline derivatives using the alkaline single cell gel electrophoresis ("comet") assay.
The alkaline (pH > 13) single cell gel electrophoresis (SCGE) assay or "comet" assay was used to evaluate for DNA damage induced… (More)
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1988
1988
Nitrosamine formation from amines applied to the skin of mice after and before exposure to nitrogen dioxide.
Skin lipids of mice exposed to NO2 contain lipid-soluble nitrosating agent(s) (NSA) that react in vitro with amines to produce… (More)
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1987
1987
An investigation of the metabolism of N-nitroso-N-methylaniline by phenobarbital- and pyrazole-induced Sprague-Dawley rat liver and esophagus derived S-9.
The metabolism and mutagenicity of the esophageal carcinogen N-nitroso-N-methylaniline (NMA) was studied using hepatic and… (More)
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1981
1981
p-Chloro-N-methylaniline demethylase activity in liver and extrahepatic tissues of the human fetus and in chick embryo liver.
We achieved a 50-fold increase in sensitivity of a fluorescence assay for p-chloro-N-methylaniline (p-CNMA) demethylase enabling… (More)
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1979
1979
Effect of inducers and inhibitors of monooxygenase on the hydroxylation of prostaglandins in the guinea pig. Evidence for several monooxygenases catalyzing omega- and omega-1-hydroxylation.
The incubation of prostaglandins (PG's) with liver microsomes from guinea pigs treated with inducers of monooxygenase (1,1,1… (More)
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1979
1979
Oral toxicity of an essential oil from myrtle and adaptive liver stimulation.
The acute oral toxicity of an essential oil from the leaves of Myrtus communis (M) in rats was 3.7 ml/kg, and 2.2 ml/kg in mice… (More)
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1975
1975
Properties of 5-aminolaevulinate synthetase and its relationship to microsomal mixed-function oxidation in the southern armyworm (Spodoptera eridania).
1. Activity of 5-aminolaevulinate synthetase was measured in the midgut and other tissues of the last larval instar of the… (More)
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1975
1975
Diazepam, ethanol and drug metabolizing enzymes in rat liver.
The effect of diazepam and/or ethanol treatment of seven days on the drug metabolizing enzymes in rat liver microsomes was… (More)
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