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4-Methoxyestrone

Known as: 4-MeE1, 4-MeOE1, 4-OMeE1 
A metabolite formed during the methylation of 4-hydroxyestrone (4-OHE1) by catechol-O-methyltransferase (COMT) and devoid of any oncogenic or… 
National Institutes of Health

Papers overview

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2018
2018
Estrogen metabolism in menopausal hormone users in the women's health initiative observational study: Does it differ between estrogen plus progestin and estrogen alone?
The WHI found an unexpected reduced breast cancer risk in women using CEE alone. We hypothesized CEE alone induces estrogen… 
2011
2011
Quantitative analysis of estrogens and estrogen metabolites in endogenous MCF-7 breast cancer cells by liquid chromatography-tandem mass spectrometry.
2007
2007
Evaluation of electrospray ionization and atmospheric pressure chemical ionization for simultaneous detection of estrone and its metabolites using high-performance liquid chromatography/tandem mass…
2001
2001
COMT Isoforms Catechol Estrogens : Comparison of Wild-Type and Variant-Methyltransferase ( COMT )-mediated Metabolism of O Catechol-Updated Version
The oxidative metabolism of 17 -estradiol (E2) and estrone (E1) to catechol estrogens (2-OHE2, 4-OHE2, 2-OHE1, and 4-OHE1) and… 
2001
2001
Catechol-O-Methyltransferase ( COMT )-mediated Metabolism of Catechol Estrogens : Comparison of Wild-Type and Variant COMT Isoforms 1
The oxidative metabolism of 17 -estradiol (E2) and estrone (E1) to catechol estrogens (2-OHE2, 4-OHE2, 2-OHE1, and 4-OHE1) and… 
1986
1986
Relative binding of certain steroids of low polarity to human sex hormone—Binding globulin: Strong binding of 2-methoxyestrone, a steroid lacking the 17β-oh group
Highly Cited
1979
Highly Cited
1979
Impact of continuously administered catechol estrogens on uterine growth and luteinizing hormone secretion.
The biological activity of a series of natural catechol estrogens was examined under conditions of continuous administration. 2… 
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