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4,7-dioxosebacic acid

National Institutes of Health

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Decanoic Acids

Papers overview

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2005
2005
Structure of Chlorobium vibrioforme 5-aminolaevulinic acid dehydratase complexed with a diacid inhibitor.
The structure of Chlorobium vibrioforme 5-aminolaevulinic acid dehydratase (ALAD) complexed with the irreversible inhibitor 4,7… 
2002
2002
Species-specific Inhibition of Porphobilinogen Synthase by 4-Oxosebacic Acid*
Porphobilinogen synthase (PBGS) catalyzes the condensation of two molecules of 5-aminolevulinic acid (ALA), an essential step in… 
Review
2002
Review
2002
5-Aminolaevulinic acid dehydratase: metals, mutants and mechanism.
5-Aminolaevulinic acid dehydratase catalyses the formation of porphobilinogen from two molecules of 5-aminolaevulinic acid. The… 
2001
2001
Mechanistic basis for suicide inactivation of porphobilinogen synthase by 4,7-dioxosebacic acid, an inhibitor that shows dramatic species selectivity.
4,7-Dioxosebacic acid (4,7-DOSA) is an active site-directed irreversible inhibitor of porphobilinogen synthase (PBGS). PBGS… 
2001
2001
The X‐ray structure of yeast 5‐aminolaevulinic acid dehydratase complexed with two diacid inhibitors
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