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4,4',6-trimethylangelicin

Known as: 4,4',6-TMA, 4,6,4'-trimethylangelicin, 2H-Furo(2,3-h)-1-benzopyran-2-one, 4,6,9-trimethyl-, (5Z,11alpha,13E,15S)- 
 
National Institutes of Health

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Related topics

1 relation

Broader (1)

Furocoumarins

Papers overview

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2014
2014
Trimethylangelicin promotes the functional rescue of mutant F508del CFTR protein in cystic fibrosis airway cells.
Cystic fibrosis transmembrane conductance regulator (CFTR) carrying the F508del mutation is retained in endoplasmic reticulum and… Expand
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2011
2011
Trimethylangelicin reduces IL-8 transcription and potentiates CFTR function.
Chronic inflammatory response in the airway tract of patients affected by cystic fibrosis is characterized by an excessive… Expand
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2002
2002
Apoptosis in leukocytes induced by UVA in the presence of 8-methoxypsoralen, chlorpromazine or 4,6,4'-trimethylangelicin.
Although 8-methoxypsoralen (8-MOP) has been successfully used in extracorporeal photochemotherapy (ECP) of several T cell… Expand
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1996
1996
The lack of efficacy of 4,6,6'-trimethylangelicin to induce immune suppression in an animal model for photopheresis: a comparison with 8-MOP.
Photopheresis is an extracorporeal form of photochemotherapy with 8-methoxypsoralen (8-MOP) and UVA (PUVA). Patients ingest 8-MOP… Expand
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1996
1996
Angular furoquinolinones, psoralen analogs: novel antiproliferative agents for skin diseases. Synthesis, biological activity, mechanism of action, and computer-aided studies.
With the aim of obtaining new potential photochemotherapeutic agents, having increased antiproliferative activity and decreased… Expand
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1995
1995
Photoinduction of micronuclei by 4,4',6-trimethylangelicin and 8-methoxypsoralen in different experimental models.
The frequencies of micronuclei induced by treatment with 4,4',6-trimethylangelicin (TMA) and 8-methoxypsoralen (8-MOP) have been… Expand
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1994
1994
Photosensitized cross-linking and cleavage of pBR322 and M13 DNA: comparison of 4,4',6-trimethylangelicin and 3-carbethoxypsoralen.
The furocourmarins 3-carbethoxypsoralen (3-CP) and 4,4',6-trimethylangelicin (TMA) were generally believed to be incapable of… Expand
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1993
1993
Furocoumarin sensitization induces DNA-protein cross-links.
The capacity of some linear and angular furocoumarins to induce DNA-protein cross-links by UVA (320-400 nm) irradiation has been… Expand
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1991
1991
Allergic contact and photocontact dermatitis due to psoralens in patients with psoriasis treated with topical PUVA.
The incidence and clinical features of allergic contact and/or photocontact dermatitis due to psoralens were examined in 371… Expand
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1991
1991
Photobinding of 8-methoxypsoralen, 4,6,4'-trimethylangelicin and chlorpromazine to Wistar rat epidermal biomacromolecules in vivo.
Photoinduced binding of drugs to endogenous biomacromolecules may cause both toxic and therapeutic effects. For example… Expand
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