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4'-azidocytidine

 
National Institutes of Health

Papers overview

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2018
2018
&NA; Ebolaviruses, marburgviruses, and henipaviruses are zoonotic pathogens belonging to the Filoviridae and Paramyxoviridae… Expand
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2017
2017
The henipaviruses Nipah virus and Hendra virus are highly pathogenic zoonotic paramyxoviruses which have caused fatal outbreaks… Expand
2010
2010
Background: R1479, a 4′-azidocytidine nucleoside analog, was developed for the treatment of Hepatitis C virus infection… Expand
2009
2009
We report the design, synthesis and evaluation of a family of ca 50 phosphoramidate ProTides of the potent anti-HCV compound 4… Expand
2009
2009
4'-Azidocytidine 3 (R1479) has been previously discovered as a potent and selective inhibitor of HCV replication targeting the… Expand
Highly Cited
2009
Highly Cited
2009
The discovery of 4'-azidocytidine (3) (R1479) (J. Biol. Chem. 2006, 281, 3793; Bioorg. Med. Chem. Lett. 2007, 17, 2570) as a… Expand
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Highly Cited
2008
Highly Cited
2008
RNA polymerases effectively discriminate against deoxyribonucleotides and specifically recognize ribonucleotide substrates most… Expand
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Highly Cited
2007
Highly Cited
2007
We report the application of our phosphoramidate ProTide technology to the ribonucleoside analogue 4'-azidouridine to generate… Expand
Highly Cited
2007
Highly Cited
2007
A series of 4'-substituted ribonucleoside derivatives has been prepared and evaluated for inhibition of hepatitis C virus (HCV… Expand
Highly Cited
2006
Highly Cited
2006
Hepatitis C virus (HCV) polymerase activity is essential for HCV replication. Targeted screening of nucleoside analogs identified… Expand
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