4'-azidocytidine

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2006-2017
0120062017

Papers overview

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2018
2018
Ebolaviruses, marburgviruses, and henipaviruses are zoonotic pathogens belonging to the Filoviridae and Paramyxoviridae families… (More)
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2017
2017
The henipaviruses Nipah virus and Hendra virus are highly pathogenic zoonotic paramyxoviruses which have caused fatal outbreaks… (More)
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2010
2010
BACKGROUND R1479, a 4'-azidocytidine nucleoside analog, was developed for the treatment of Hepatitis C virus infection… (More)
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2009
2009
We report the design, synthesis and evaluation of a family of ca 50 phosphoramidate ProTides of the potent anti-HCV compound 4… (More)
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2009
2009
4'-Azidocytidine 3 (R1479) has been previously discovered as a potent and selective inhibitor of HCV replication targeting the… (More)
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2009
2009
The discovery of 4'-azidocytidine (3) (R1479) (J. Biol. Chem. 2006, 281, 3793; Bioorg. Med. Chem. Lett. 2007, 17, 2570) as a… (More)
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2008
2008
RNA polymerases effectively discriminate against deoxyribonucleotides and specifically recognize ribonucleotide substrates most… (More)
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2007
2007
We report the application of our phosphoramidate ProTide technology to the ribonucleoside analogue 4'-azidouridine to generate… (More)
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2007
2007
A series of 4'-substituted ribonucleoside derivatives has been prepared and evaluated for inhibition of hepatitis C virus (HCV… (More)
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Highly Cited
2006
Highly Cited
2006
Hepatitis C virus (HCV) polymerase activity is essential for HCV replication. Targeted screening of nucleoside analogs identified… (More)
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