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R1479

National Institutes of Health

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Related topics

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Broader (1)

4'-azidocytidine

Papers overview

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Review
2010
Review
2010
The standard treatment of HCV infection with pegylated interferon-a2a or -a2b and ribavirin is effective in <50%
The standard treatment of HCV infection with pegylated interferon-a2a or -a2b and ribavirin is effective in <50% of HCV genotype… 
2009
2009
Chemical stability of 4′-azidocytidine and its prodrug balapiravir
Background: R1479, a 4′-azidocytidine nucleoside analog, was developed for the treatment of Hepatitis C virus infection… 
2008
2008
Physicochemical properties of the nucleoside prodrug R1626 leading to high oral bioavailability.
The nucleoside analog R1479 is a potent and highly selective inhibitor of NS5b-directed hepatitis C virus (HCV) RNA polymerase in… 
2008
2008
851 ANTIVIRAL POTENCY OF R1479, ACTIVE COMPOUND DERIVED IN VIVO FROM PRODRUG R1626, DEMONSTRATED ACROSS HCV GENOTYPES 1-6 IN NS5B RECOMBINANT ENZYMES AND HCV REPLICONS
2007
2007
[790] IN VITRO RESISTANCE SELECTION TO THE HCV NUCLEOSIDE POLYMERASE INHIBITOR R1479 AND TO THE PROTEASE INHIBITOR VX-950
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