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3-tritylthio-L-alanine

Known as: S-(triphenylmethyl)-L-cysteine, S-Trityl-L-cysteine, Tritylcysteine 
A derivative of cysteine with antimitotic activity and potential antineoplastic activity. (NCI04)
National Institutes of Health

Related topics

Related topics

4 relations

Broader (1)

Cysteine
NCIt Antineoplastic Agent Terminologyanalogs & derivatives

Narrower (1)

NSC 83265

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Silylium ion-promoted dehydrogenative cyclization: synthesis of silicon-containing compounds derived from alkynes.
Treatment of dialkylbenzylsilane (1) with trityl tetrakis(pentafluorophenyl)borate (TPFPB) in the presence of terminal or… 
2011
2011
Synthesis of bridged molecular gyroscopes with closed topologies: triple one-pot macrocyclization.
We describe the synthesis and characterization of six bridged molecular gyroscopes with m-alkoxy-substituted trityl stators and… 
Highly Cited
2008
Highly Cited
2008
Structure-activity relationship of S-trityl-L-cysteine analogues as inhibitors of the human mitotic kinesin Eg5.
The human kinesin Eg5 is a potential drug target for cancer chemotherapy. Eg5 specific inhibitors cause cells to block in mitosis… 
2006
2006
The synthesis of new weakly coordinating diborate anions: anion stability as a function of linker structure and steric bulk.
The successive addition of KCN and Ph3CCl to B(C6F4-C6F5-2)3 (PBB) affords triphenylmethyl salts of the [NC-PBB]- anion. By… 
2004
2004
In situ deprotection and assembly of s-tritylalkanethiols on gold yields monolayers comparable to those prepared directly from alkanethiols.
In this paper we describe a systematic study comparing the properties of self-assembled monolayers (SAMs) formed by in situ… 
2001
2001
Reductive demercuration in deprotection of trityl thioethers, trityl amines, and trityl ethers.
A room-temperature deprotection method of trityl amines, -ethers, and -thioethers is presented, based on coupling of metal acid… 
1998
1998
Efficient Solid-Phase Synthesis of Peptide-Substituted Alkanethiols for the Preparation of Substrates That Support the Adhesion of Cells.
Self-assembled monolayers that present short peptide ligands are an important class of model substrates for studies of the… 
1993
1993
Structure effects of ion pair separation: planar and pyramidal sulfur and silicon substituted carbanions
The conversion of a lithium reagent to a free carbanion (contact to separated ion pairs) is expected to cause structural changes… 
1987
1987
The synthesis of protected 5'-mercapto-2',5'-dideoxyribonucleoside-3'-O-phosphoramidites; uses of 5'-mercapto-oligodeoxyribonucleotides.
The syntheses of the four novel, base protected 5'-(S-triphenylmethyl)mercapto-2',5'-dideoxyribonucleoside-3 '-O-(2-cyanoethyl N… 
1965
1965
On cysteine and cystine peptides. 3. Synthesis of a fragment of insulin containing the intrachain disulfide bridge.
The application of methods developed mostly in this laboratory permitted the synthesis of the fully S,Nprotected heptapeptides N… 
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