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3-methyloxindole

 

Topic mentions per year

Topic mentions per year

1965-2015
02419652015

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2 relations

Broader (2)

3-methyl-2-oxindoleIndoles

Related mentions per year

Related mentions per year

1941-2018
19401960198020002020
3-methyloxindole
Indoles
3-methyl-2-oxindole

Papers overview

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2007
2007
Metabolism and bioactivation of 3-methylindole by human liver microsomes.
Metabolism and bioactivation of 3-methylindole (3MI) were investigated in human liver microsomes. The metabolism of two deuterium… (More)
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2006
2006
The role of CYP2A and CYP2E1 in the metabolism of 3-methylindole in primary cultured porcine hepatocytes.
The accumulation of 3-methylindole (3MI) in uncastrated male pigs (boars) is a major cause of boar taint, which negatively… (More)
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2001
2001
Selective dehydrogenation/oxygenation of 3-methylindole by cytochrome p450 enzymes.
3-Methylindole (3 MI) is a selective pulmonary toxicant, and cytochrome P450 (P450) bioactivation of 3 MI, through hydroxylation… (More)
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1999
1999
Specific dehydrogenation of 3-methylindole and epoxidation of naphthalene by recombinant human CYP2F1 expressed in lymphoblastoid cells.
3-Methylindole (3MI) is a naturally occurring pulmonary toxin that requires metabolic activation. Previous studies have shown… (More)
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1999
1999
Identification of phase I metabolites of 3-methylindole produced by pig liver microsomes.
A study was conducted to investigate qualitative and quantitative aspects of the phase I metabolism of 3-methylindole (3MI) by… (More)
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1998
1998
Evidence supporting the formation of 2,3-epoxy-3-methylindoline: a reactive intermediate of the pneumotoxin 3-methylindole.
The existence of a cytochrome P450-dependent 2,3-epoxide of the potent pneumotoxin 3-methylindole was indirectly confirmed using… (More)
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1996
1996
Metabolism of 3-methylindole by vaccinia-expressed P450 enzymes: correlation of 3-methyleneindolenine formation and protein-binding.
The toxicity of 3-methylindole (3 MI), a selective pneumotoxin, is dependent upon cytochrome P450-mediated bioactivation 3. Using… (More)
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1992
1992
Metabolism of 3-methylindole by a methanogenic consortium.
A methanogenic 3-methylindole (3-MI)-degrading consortium, enriched from wetland soil, completely mineralized 3-MI. Degradation… (More)
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1989
1989
Isolation and identification of 3-hydroxy-3-methyloxindole, the major murine metabolite of 3-methylindole.
3-Methylindole (3MI) is pneumotoxic to ruminants and rodents subsequent to metabolic oxidative activation by cytochrome P-450… (More)
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1967
1967
Inhibitory oxidation products of indole-3-acetic Acid: 3-hydroxymethyloxindole and 3-methyleneoxindole as plant metabolites.
Extracts of pea seedlings (Pisum sativum, variety Alaska) oxidize indole-3-acetic acid to a bacteriostatic compound which has… (More)
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