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3-isobutyl-8-pyrrolidinoxanthine
Known as:
IPDX cpd
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Pyrrolidinones
Xanthines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Effect of A2B Adenosine Receptor Gene Ablation on Adenosine-Dependent Regulation of Proinflammatory Cytokines
Sergey Ryzhov
,
Rinat Zaynagetdinov
,
+4 authors
I. Feoktistov
Journal of Pharmacology and Experimental…
2008
Corpus ID: 14058136
Pharmacological studies suggest that A2B adenosine receptors mediate proinflammatory effects of adenosine. This concept was…
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Highly Cited
2004
Highly Cited
2004
Adenosine-Activated Mast Cells Induce IgE Synthesis by B Lymphocytes: An A2B-Mediated Process Involving Th2 Cytokines IL-4 and IL-13 with Implications for Asthma12
Sergey Ryzhov
,
A. Goldstein
,
A. Matafonov
,
D. Zeng
,
I. Biaggioni
,
I. Feoktistov
Journal of Immunology
2004
Corpus ID: 19668772
Adenosine provokes bronchoconstriction in asthmatics through acute activation of mast cells, but its potential role in chronic…
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2003
2003
A2A and A3 receptors mediate the adenosine‐induced relaxation in spontaneously active possum duodenum in vitro
C. Woods
,
J. Toouli
,
G. Saccone
British Journal of Pharmacology
2003
Corpus ID: 5796256
The aim of this study was to define the P1 purinergic receptors that regulate spontaneous or adenosine‐induced duodenal motor…
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Highly Cited
2001
Highly Cited
2001
Inhibition of human mast cell activation with the novel selective adenosine A(2B) receptor antagonist 3-isobutyl-8-pyrrolidinoxanthine (IPDX)(2).
I. Feoktistov
,
E. Garland
,
+4 authors
I. Biaggioni
Biochemical Pharmacology
2001
Corpus ID: 39878843
Highly Cited
2001
Highly Cited
2001
Proliferation, migration, and ERK activation in human retinal endothelial cells through A(2B) adenosine receptor stimulation.
M. Grant
,
M. I. Davis
,
S. Caballero
,
I. Feoktistov
,
I. Biaggioni
,
L. Belardinelli
Investigative Ophthalmology and Visual Science
2001
Corpus ID: 22717018
PURPOSE The nucleoside adenosine has been implicated in angiogenesis. A previous study demonstrated that activation of the A(2B…
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2001
2001
Adenosine receptor antagonists and retinal neovascularization in vivo.
R. P. Mino
,
P. Spoerri
,
+4 authors
M. Grant
Investigative Ophthalmology and Visual Science
2001
Corpus ID: 11174696
PURPOSE The role of adenosine receptor (AdoR) antagonists in human retinal endothelial cell function in vitro has previously been…
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