Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

3-isobutyl-8-pyrrolidinoxanthine

Known as: IPDX cpd 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

PyrrolidinonesXanthines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Effect of A2B Adenosine Receptor Gene Ablation on Adenosine-Dependent Regulation of Proinflammatory Cytokines
Pharmacological studies suggest that A2B adenosine receptors mediate proinflammatory effects of adenosine. This concept was… Expand
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • table 2
Highly Cited
2004
Highly Cited
2004
Adenosine-Activated Mast Cells Induce IgE Synthesis by B Lymphocytes: An A2B-Mediated Process Involving Th2 Cytokines IL-4 and IL-13 with Implications for Asthma12
Adenosine provokes bronchoconstriction in asthmatics through acute activation of mast cells, but its potential role in chronic… Expand
  • figure 1
  • figure 2
  • table I
  • figure 3
  • figure 4
2003
2003
A2A and A3 receptors mediate the adenosine‐induced relaxation in spontaneously active possum duodenum in vitro
The aim of this study was to define the P1 purinergic receptors that regulate spontaneous or adenosine‐induced duodenal motor… Expand
Highly Cited
2001
Highly Cited
2001
Inhibition of human mast cell activation with the novel selective adenosine A(2B) receptor antagonist 3-isobutyl-8-pyrrolidinoxanthine (IPDX)(2).
The antiasthmatic drug enprofylline was the first known selective, though not potent, A(2B) antagonist. On the basis of structure… Expand
Highly Cited
2001
Highly Cited
2001
Proliferation, migration, and ERK activation in human retinal endothelial cells through A(2B) adenosine receptor stimulation.
PURPOSE The nucleoside adenosine has been implicated in angiogenesis. A previous study demonstrated that activation of the A(2B… Expand
2001
2001
Adenosine receptor antagonists and retinal neovascularization in vivo.
PURPOSE The role of adenosine receptor (AdoR) antagonists in human retinal endothelial cell function in vitro has previously been… Expand
  • table 1
  • figure 1
  • figure 2
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE