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3-hydroxyacetaminophen

Known as: acetamide, N-(3,4-dihydroxyphenyl)- 
National Institutes of Health

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3'-hydroxyacetaminophen

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Acetaminophen
analogs & derivatives

Papers overview

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2019
2019
Kinetic study of colored species formation during paracetamol removal from water in a semicontinuous ozonation contactor.
Highly Cited
1998
Highly Cited
1998
Role of CYP2A5 and 2G1 in acetaminophen metabolism and toxicity in the olfactory mucosa of the Cyp1a2(-/-) mouse.
1994
1994
Preferred orientations in the binding of 4'-hydroxyacetanilide (acetaminophen) to cytochrome P450 1A1 and 2B1 isoforms as determined by 13C- and 15N-NMR relaxation studies.
The widely used analgesic/antipyretic agent 4'-hydroxyacetanilide (acetaminophen, APAP) is oxidized by cytochromes P450 to a… 
1990
1990
Dysmorphogenesis elicited by microinjected acetaminophen analogs and metabolites in rat embryos cultured in vitro.
Direct additions of acetaminophen (APAP), 3,5-dimethylacetaminophen, 3-hydroxyacetaminophen or 3-methoxyacetaminophen to the… 
Highly Cited
1988
Highly Cited
1988
Cytochrome P-450 isozyme selectivity in the oxidation of acetaminophen.
Highly purified isozymes of cytochrome P-450 catalyzed the formation of 3-glutathion-S-ylacetaminophen (GS-APAP) and 3… 
1986
1986
The metabolism of 2- and 3-hydroxyacetanilide. Determination of metabolic products by liquid chromatography/electrochemistry.
The metabolism of 2- and 3-hydroxyacetanilide was examined in incubations with mouse liver microsomes. Metabolic products were… 
1984
1984
The formation and toxicity of catechol metabolites of acetaminophen in mice.
Acetaminophen is metabolized to a catechol, 3'-hydroxy-4'-hydroxyacetanilide (3-hydroxyacetaminophen), by mouse liver microsomes… 
Highly Cited
1982
Highly Cited
1982
Analysis of acetaminophen metabolites in urine by high-performance liquid chromatography with UV and amperometric detection.
Highly Cited
1980
Highly Cited
1980
3-Hydroxyacetaminophen: a microsomal metabolite of acetaminophen. Evidence against an epoxide as the reactive metabolite of acetaminophen.
3-Hydroxyacetaminophen has been isolated and identified as a microsomal metabolite of acetaminophen. Analysis of the metabolite… 
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