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3-amino-2-hydroxy-5-methylhexanoic acid
Known as:
AHMHA
, norstatine
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
6-Aminocaproic Acid
Aminocaproates
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Synthesis and structural studies of pentacycloundecane-based HIV-1 PR inhibitors: a hybrid 2D NMR and docking/QM/MM/MD approach.
Maya M. Makatini
,
Katja Petzold
,
+11 authors
T. Govender
European journal of medicinal chemistry
2011
Corpus ID: 19278641
2011
2011
Pentacycloundecane-based inhibitors of wild-type C-South African HIV-protease.
Maya M. Makatini
,
Katja Petzold
,
+8 authors
T. Govender
Bioorganic & Medicinal Chemistry Letters
2011
Corpus ID: 21509173
2007
2007
Design and synthesis of BACE1 inhibitors containing a novel norstatine derivative (2R,3R)-3-amino-2-hydroxy-4-(phenylthio)butyric acid.
Z. Ziora
,
S. Kasai
,
+4 authors
Y. Kiso
Bioorganic & Medicinal Chemistry Letters
2007
Corpus ID: 22585658
2006
2006
The Potential of P1 Site Alterations in Peptidomimetic Protease Inhibitors as Suggested by Virtual Screening and Explored by the Use of CC‐Coupling Reagents
Steffen Weik
,
Torsten Luksch
,
+6 authors
J. Rademann
ChemMedChem
2006
Corpus ID: 32242394
A synthetic concept is presented that allows the construction of peptide isostere libraries through polymer‐supported C‐acylation…
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2001
2001
Design, synthesis, and biological evaluation of HIV/FIV protease inhibitors incorporating a conformationally constrained macrocycle with a small P3' residue.
Chi Ching Mak
,
Van-Duc Le
,
Y. Lin
,
John H. Elder
,
Chi-Huey Wong
Bioorganic & Medicinal Chemistry Letters
2001
Corpus ID: 13243603
1992
1992
Crystallization and preliminary X-ray analysis of complexes of peptide inhibitors with human recombinant and mouse submandibular renins.
M. Badasso
,
C. Frazão
,
+7 authors
H. Miyazaki
Journal of Molecular Biology
1992
Corpus ID: 12858501
1990
1990
Synthesis and structure-activity relationships of human renin inhibitors designed from angiotensinogen transition state.
K. Iizuka
,
T. Kamijo
,
+7 authors
T. Yamaguchi
Chemical and pharmaceutical bulletin
1990
Corpus ID: 23266325
The synthesis and the structure-activity relationships of renin inhibitors designed from the angiotensinogen transition state are…
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1990
1990
Synthesis of human renin inhibitory peptides, angiotensinogen transition-state analogs containing a retro-inverso amide bond.
H. Harada
,
K. Iizuka
,
+7 authors
H. Umeyama
Chemical and pharmaceutical bulletin
1990
Corpus ID: 38456444
The experimental details for the synthesis of human renin inhibitors are described. In order to avoid metabolic degradation of…
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Highly Cited
1988
Highly Cited
1988
New human renin inhibitors containing an unnatural amino acid, norstatine.
K. Iizuka
,
T. Kamijo
,
T. Kubota
,
K. Akahane
,
H. Umeyama
,
Y. Kiso
Journal of Medicinal Chemistry
1988
Corpus ID: 38786520
1982
1982
Renin inhibitors. Substitution of the leucyl residues of Leu-Leu-Val-Phe-OCH3 with 3-amino-2-hydroxy-5-methylhexanoic acid.
R. Johnson
Journal of Medicinal Chemistry
1982
Corpus ID: 28080749
The 2S,3S and 2R,3S diastereoisomers of the hydroxy amino acid 3-amino-2-hydroxy-5-methylhexanoic acid (AHMHA) were synthesized…
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