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3',5'-Cyclic-GMP Phosphodiesterases

Known as: Phosphodiesterases, 3',5'-Cyclic-GMP, 3',5'-Cyclic-GMP Phosphodiesterases [Chemical/Ingredient], 3',5'-Cyclic GMP Phosphodiesterase 
Enzymes that catalyze the hydrolysis of cyclic GMP to yield guanosine-5'-phosphate.
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
MrkH, a Novel c-di-GMP-Dependent Transcriptional Activator, Controls Klebsiella pneumoniae Biofilm Formation by Regulating Type 3 Fimbriae Expression
Klebsiella pneumoniae causes significant morbidity and mortality worldwide, particularly amongst hospitalized individuals. The… 
Highly Cited
2009
Highly Cited
2009
Cyclic GMP Signaling Is Involved in the Luteinizing Hormone-Dependent Meiotic Maturation of Mouse Oocytes1
It is well established that cAMP signaling is an important regulator of the oocyte meiotic cell cycle. Conversely, the function… 
Highly Cited
1993
Highly Cited
1993
Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase.
The guanosine triphosphate (GTP)-binding protein Ras functions in regulating growth and differentiation; however, little is known… 
Highly Cited
1991
Highly Cited
1991
Excitatory Amino Acid Receptors Coupled to the Nitric Oxide/Cyclic GMP Pathway in Rat Cerebellum During Development
Abstract: The coupling of excitatory amino acid receptors to the formation of nitric oxide (NO) from arginine during the… 
Highly Cited
1989
Highly Cited
1989
N‐Methyl‐D‐Aspartate Receptors and Ethanol: Inhibition of Calcium Flux and Cyclic GMP Production
Abstract: Measurements of calcium uptake and cyclic GMP production by cerebellar granule cells grown in primary culture… 
Highly Cited
1989
Highly Cited
1989
Regulation of intracellular Ca2+ levels in cultured vascular smooth muscle cells. Reduction of Ca2+ by atriopeptin and 8-bromo-cyclic GMP is mediated by cyclic GMP-dependent protein kinase.
Primary rat aortic cells, when treated with arginine vasopressin or depolarizing concentrations of K+, responded to atriopeptin… 
Highly Cited
1989
Highly Cited
1989
Activation of a cytosolic ADP-ribosyltransferase by nitric oxide-generating agents.
Highly Cited
1983
Highly Cited
1983
A role of calcium-activated phospholipid-dependent protein kinase in human platelet activation. Comparison of thrombin and collagen actions.
Highly Cited
1977
Highly Cited
1977
Malakoplakia: evidence for monocyte lysosomal abnormality correctable by cholinergic agonist in vitro and in vivo.
We studied monocyte function in a case of malakoplakia in an attempt to characterize the immune defect in this condition. Our… 
Highly Cited
1972
Highly Cited
1972
Role of muscarinic cholinergic receptors in regulation of guanosine 3':5'-cyclic monophosphate content in mammalian brain, heart muscle, and intestinal smooth muscle.
Effects of acetylcholine and of agents that mimic or block its physiological actions have been studied upon concentrations of… 
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