2C4 antibody

Known as: 2C4, MoAb 2C4, Monoclonal Antibody 2C4 
 

Topic mentions per year

Topic mentions per year

1989-2018
02419892018

Papers overview

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2008
2008
2C4 (Pertuzumab, Omnitarg) is a monoclonal antibody targeting p185her2/neu, which is overexpressed in 30% of invasive breast… (More)
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2007
2007
Pertuzumab (Omnitarg, rhuMab 2C4) is a humanized monoclonal antibody, which inhibits HER2 dimerization. Because it has shown some… (More)
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2005
2005
BACKGROUND Human epidermal growth factor receptor 2 (HER2) is overexpressed in 25-30% of ovarian carcinoma cases and a… (More)
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Highly Cited
2004
Highly Cited
2004
We have determined the 3.2 A X-ray crystal structure of the extracellular domain of the human epidermal growth factor receptor 2… (More)
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2004
2004
Due to heterodimerization and a variety of stimulating ligands, the ErbB receptor system is both diverse and flexible, which… (More)
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2004
2004
R-etodolac, a nonsteroidal anti-inflammatory drug, inhibits the progression of CWRSA6 androgen-independent and LuCaP-35 androgen… (More)
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Highly Cited
2002
Highly Cited
2002
ErbB2 is a ligand-less member of the ErbB receptor family that functions as a coreceptor with EGFR, ErbB3, and ErbB4. Here, we… (More)
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Highly Cited
2001
Highly Cited
2001
HER2 is a ligand-less tyrosine kinase receptor of the ErbB family that is frequently overexpressed in breast cancer. It undergoes… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND & AIMS The cyclooxygenase 2 (COX-2) and ErbB/HER pathways are important modulators of cancer cell growth. We sought to… (More)
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Highly Cited
1995
Highly Cited
1995
The ability of sensory axons to stimulate Schwann cell proliferation by contact was established in the 1970s. Although the… (More)
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