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24,25-dihydrolanosterol

National Institutes of Health

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lanostenol

Papers overview

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Highly Cited
2008
Highly Cited
2008
Effectors of Rapid Homeostatic Responses of Endoplasmic Reticulum Cholesterol and 3-Hydroxy-3-methylglutaryl-CoA Reductase*
The cholesterol content of the endoplasmic reticulum (ER) and the activity of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR… 
1994
1994
Selective inhibition of mammalian lanosterol 14 alpha-demethylase by RS-21607 in vitro and in vivo.
The discovery of selective lanosterol 14 alpha-demethylase inhibitors may lead to novel hypolipidemic drugs. RS-21607, (2S,4S… 
1992
1992
Complete replacement of membrane cholesterol with 4,4',14-trimethyl sterols in a human T cell line defective in lanosterol demethylation.
1991
1991
Purification and characterization of cytochrome P-45014DM (lanosterol 14α-demethylase) from pig liver microsomes
1991
1991
Role of the side chain of lanosterol in substrate recognition and catalytic activity of lanosterol 14 alpha-demethylase (cytochrome P-450 (14DM)) of yeast.
Highly Cited
1989
Highly Cited
1989
Perturbation of sterol biosynthesis by itraconazole and ketoconazole in Leishmania mexicana mexicana infected macrophages.
1988
1988
In vitro effects of oxygenated lanosterol derivatives on cholesterol biosynthesis from 24,25-dihydrolanosterol.
The effects of oxygenated lanosterol derivatives (1-27, 5μM) including 32-oxygenated lanosterol derivatives on cholesterol… 
Highly Cited
1984
Highly Cited
1984
Cytochrome P-450-dependent oxidation of lanosterol in cholesterol biosynthesis. Microsomal electron transport and C-32 demethylation.
1983
1983
Metabolism of mevalonic acid in cell-free homogenates of bovine retinas. Formation of novel isoprenoid acids.
1963
1963
Studies of cholesterol biosynthesis. IV. Reduction of lanosterol to 24,25-dihydrolanosterol by rat liver homogenates.
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