20-alpha-Dihydroprogesterone

Known as: 20-alpha-Hydroxyprogesterone, Pregn-4-en-3-one, 20-alpha-hydroxy-, 20alpha Hydroxypregn 4 Ene 3 One 
A biologically active 20-alpha-reduced metabolite of PROGESTERONE. It is converted from progesterone to 20-alpha-hydroxypregn-4-en-3-one by the 20… (More)
National Institutes of Health

Related topics

Related topics

12 relations

Narrower (1)

3-hydroxypregn-4-en-20-one
In BloodProcess of secretionagonistsanalogs & derivatives
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Broader (2)

ProgesteroneProgestins

Papers overview

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Highly Cited
2007
Highly Cited
2007
Progesterone and its derivatives are neuroprotective agents in experimental diabetic neuropathy: A multimodal analysis
One important complication of diabetes is damage to the peripheral nervous system. However, in spite of the number of studies on… (More)
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Highly Cited
2006
Highly Cited
2006
Decreased Cerebrospinal Fluid Allopregnanolone Levels in Women with Posttraumatic Stress Disorder
BACKGROUND Alterations in the gamma-amino-butyric acid (GABA) neurotransmitter system have been identified in some populations… (More)
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Highly Cited
2004
Highly Cited
2004
Reduced progesterone metabolites protect rat hippocampal neurones from kainic acid excitotoxicity in vivo.
The ovarian hormone progesterone is neuroprotective in some animal models of neurodegeneration. Progesterone actions in the brain… (More)
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Highly Cited
2001
Highly Cited
2001
Brain 5alpha-dihydroprogesterone and allopregnanolone synthesis in a mouse model of protracted social isolation.
Allopregnanolone (ALLO), is a brain endogenous neurosteroid that binds with high affinity to gamma-aminobutyric acid type A (GABA… (More)
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Review
2001
Review
2001
The socially-isolated mouse: a model to study the putative role of allopregnanolone and 5α-dihydroprogesterone in psychiatric disorders
Allopregnanolone (3alpha,5alpha-TH PROG) and 5alpha-dihydroprogesterone (5alpha-DH PROG), the two most important neuroactive… (More)
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1999
1999
Patterns of urinary and fecal steroid excretion during the ovarian cycle and pregnancy in the African elephant (Loxodonta africana).
The aims of the present study were to (i) determine the relative abundance of the 5alpha-reduced progestins 5alpha-pregnane-3-ol… (More)
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Highly Cited
1995
Highly Cited
1995
Reliability of Spike Timing in Neocortical Neurons
screen of the microscope. Between 150 to 300 nerve fibers were analyzed per cross section. 13. C. F. Eldridge, M. Bartlett, R. P… (More)
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Highly Cited
1993
Highly Cited
1993
Expression cloning and characterization of human 17 beta-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20 alpha-hydroxysteroid dehydrogenase activity.
17 beta-Hydroxysteroid dehydrogenase (17 beta-HSD) is an enzyme crucial to the regulation of intracellular levels of biologically… (More)
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1992
1992
Measurement of urinary oestrogens and 20 alpha-dihydroprogesterone during ovarian cycles of black (Diceros bicornis) and white (Ceratotherium simum) rhinoceroses.
The development of a sensitive enzyme-immunoassay for 20 alpha-dihydroprogesterone (20 alpha-DHP) and its use in determining… (More)
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1975
1975
Progesterone, 20 alpha-dihydroprogesterone and 20 beta-dihydroprogesterone in mother and child at birth.
In 14 healthy pregnant women at term progesterone (P) and 20 alpha-dihydroprogesterone (20 alpha-DHP) were determined by… (More)
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